Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Holy Cross (Louisville) | away | L | 51–53 | 0-1 | ||
| Tue, Dec 5, 2000 | Moore | home | W | 61–35 | 1-1 | ||
| Fri, Dec 8, 2000 | Fern Creek | away | W | 62–39 | 2-1 | ||
| Sun, Dec 10, 2000 | Sacred Heart | at trinity | L | 48–65 | 2-2 | ||
| Wed, Dec 20, 2000 | South Oldham | at male | W | 62–30 | 3-2 | Male Holiday Classic | |
| Thu, Dec 21, 2000 | Muhlenberg South | at male | W | 63–40 | 4-2 | Male Holiday Classic | |
| Fri, Dec 22, 2000 | Male | away | L | 53–56 | 4-3 | Male Holiday Classic | |
| Sat, Dec 23, 2000 | Butler | at male | W | 54–53 | 5-3 | Male Holiday Classic | |
| Wed, Dec 27, 2000 | Boyd County | at east carter | W | 68–39 | 6-3 | Queen of the Bluegrass | |
| Thu, Dec 28, 2000 | Newport | at east carter | W | 59–48 | 7-3 | Queen of the Bluegrass | |
| Fri, Dec 29, 2000 | Harrison County | at east carter | W | 52–36 | 8-3 | Queen of the Bluegrass | |
| Sat, Dec 30, 2000 | Estill County | at east carter | W | 59–46 | 9-3 | Queen of the Bluegrass (championship) | |
| Sat, Dec 30, 2000 | Paul Laurence Dunbar | at east carter | W | 55–38 | 10-3 | Queen of the Bluegrass | |
| Fri, Jan 5, 2001 | Bullitt Central | away | W | 66–64 | 11-3 | (overtime) | |
| Tue, Jan 9, 2001 | Male | home | L | 52–59 | 11-4 | ||
| Fri, Jan 12, 2001 | DuPont Manual | home | L | 49–57 | 11-5 | ||
| Tue, Jan 16, 2001 | Waggener | away | W | 69–14 | 12-5 | ||
| Fri, Jan 19, 2001 | Ballard | away | W | 45–35 | 13-5 | ||
| Wed, Jan 24, 2001 | Male | at louisville gardens | L | 42–50 | 13-6 | Louisville Invitational Tournament | |
| Tue, Jan 30, 2001 | Jeffersontown | home | |||||
| Fri, Feb 2, 2001 | Seneca | home | W | 72–44 | 14-6 | ||
| Sun, Feb 4, 2001 | Holy Rosary | home | W | 54–41 | 15-6 | ||
| Fri, Feb 9, 2001 | Atherton | away | W | 40–38 | 16-6 | ||
| Tue, Feb 13, 2001 | Eastern | home | W | 64–50 | 17-6 | ||
| Thu, Feb 15, 2001 | Oldham County | away | L | 45–53 | 17-7 | ||
| Fri, Feb 16, 2001 | Mercy Academy | at mercy | W | 66–46 | 18-7 | ||
| Wed, Feb 21, 2001 | Central Hardin | away | W | 53–37 | 19-7 | ||
| Fri, Feb 23, 2001 | Presentation | at spalding university | L | 48–58 | 19-8 | ||
| Tue, Feb 27, 2001 | Atherton | home | W | 71–22 | 20-8 | 2001 26th District Girls Basketball Tournament | |
| Fri, Mar 2, 2001 | Seneca | home | W | 60–40 | 21-8 | 2001 26th District Girls Basketball Tournament | |
| Wed, Mar 7, 2001 | Mercy Academy | at trinity (louisville) | L | 59–69 | 21-9 | 2001 7th Region Girls Basketball Tournament |