Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Anderson County | away | W | 53–50 | 1-0 | ||
| Fri, Dec 1, 2000 | Oldham County | home | L | 42–55 | 1-1 | ||
| Tue, Dec 5, 2000 | Spencer County | home | L | 55–58 | 1-2 | ||
| Fri, Dec 8, 2000 | Bullitt East | home | L | 47–55 | 1-3 | ||
| Tue, Dec 12, 2000 | North Bullitt | away | W | 57–36 | 2-3 | ||
| Fri, Dec 15, 2000 | Meade County | home | W | 46–40 | 3-3 | ||
| Wed, Dec 20, 2000 | Ballard | at north bullitt | L | 49–59 | 3-4 | First Citizens Bank Classic | |
| Thu, Dec 21, 2000 | LaRue County | at north bullitt | W | 49–36 | 4-4 | First Citizens Bank Classic | |
| Fri, Dec 22, 2000 | Doss | at north bullitt | W | 67–48 | 5-4 | First Citizens Bank Classic | |
| Thu, Dec 28, 2000 | Henry County | at carroll county | W | 58–46 | 6-4 | Lady Panther Shootout | |
| Fri, Dec 29, 2000 | Grant County | at carroll county | W | 68–30 | 7-4 | Lady Panther Shootout | |
| Sat, Dec 30, 2000 | Carroll County | away | W | 67–46 | 8-4 | Lady Panther Shootout (championship) | |
| Fri, Jan 5, 2001 | Assumption | home | L | 64–66 | 8-5 | (overtime) | |
| Mon, Jan 8, 2001 | South Oldham | away | W | 68–56 | 9-5 | ||
| Fri, Jan 12, 2001 | North Bullitt | home | W | 45–38 | 10-5 | ||
| Fri, Jan 19, 2001 | Bullitt East | home | L | 54–57 | 10-6 | ||
| Tue, Jan 23, 2001 | Spencer County | away | W | 54–43 | 11-6 | ||
| Thu, Jan 25, 2001 | Shelby County | away | L | 39–84 | 11-7 | ||
| Wed, Jan 31, 2001 | Southern | home | W | 75–40 | 12-7 | ||
| Sat, Feb 3, 2001 | Scott County | home | L | 52–61 | 12-8 | ||
| Tue, Feb 6, 2001 | Henry County | home | W | 54–46 | 13-8 | ||
| Thu, Feb 8, 2001 | Doss | home | W | 73–50 | 14-8 | ||
| Mon, Feb 12, 2001 | Elizabethtown | away | L | 48–72 | 14-9 | ||
| Thu, Feb 15, 2001 | Bardstown | away | L | 44–54 | 14-10 | ||
| Mon, Feb 19, 2001 | Bethlehem | home | W | 49–48 | 15-10 | ||
| Thu, Feb 22, 2001 | Nelson County | away | W | 64–60 | 16-10 | ||
| Fri, Feb 23, 2001 | Beth Haven | home | W | 66–34 | 17-10 | ||
| Thu, Mar 1, 2001 | Spencer County | at bullitt east | W | 51–42 | 18-10 | 2001 29th District Girls Basketball Tournament | |
| Sat, Mar 3, 2001 | North Bullitt | at bullitt east | W | 49–23 | 19-10 | 2001 29th District Girls Basketball Tournament | |
| Wed, Mar 7, 2001 | Trimble County | at shelby county | W | 63–61 | 20-10 | 2001 8th Region Girls Basketball Tournament | |
| Mon, Mar 12, 2001 | Scott County | at shelby county | L | 58–60 | 20-11 | 2001 8th Region Girls Basketball Tournament |