Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 28, 2000 | Eminence | away | W | 93–25 | 1-0 | ||
| Fri, Dec 8, 2000 | Gallatin County | away | W | 54–46 | 2-0 | ||
| Sat, Dec 9, 2000 | Spencer County | home | L | 39–54 | 2-1 | ||
| Mon, Dec 11, 2000 | South Oldham | away | W | 49–46 | 3-1 | ||
| Thu, Dec 14, 2000 | Henry County | home | W | 48–34 | 4-1 | ||
| Tue, Dec 19, 2000 | Owen County | away | W | 54–53 | 5-1 | ||
| Fri, Dec 22, 2000 | Trimble County | home | L | 43–45 | 5-2 | ||
| Thu, Dec 28, 2000 | Grant County | home | W | 48–34 | 6-2 | Lady Panther Shootout | |
| Fri, Dec 29, 2000 | Henry County | home | W | 59–38 | 7-2 | Lady Panther Shootout | |
| Sat, Dec 30, 2000 | Bullitt Central | home | L | 46–67 | 7-3 | Lady Panther Shootout (championship) | |
| Fri, Jan 5, 2001 | Williamstown | away | W | 69–51 | 8-3 | ||
| Thu, Jan 11, 2001 | Williamstown | at owen county | L | 44–56 | 8-4 | 8th Region All A Classic (1st round) | |
| Tue, Jan 16, 2001 | Eminence | home | W | 79–30 | 9-4 | ||
| Tue, Jan 23, 2001 | Henry County | away | W | 46–37 | 10-4 | ||
| Mon, Jan 29, 2001 | Oldham County | home | L | 44–73 | 10-5 | ||
| Fri, Feb 2, 2001 | Grant County | home | W | 80–34 | 11-5 | ||
| Sat, Feb 3, 2001 | Spencer County | away | W | 64–60 | 12-5 | ||
| Tue, Feb 6, 2001 | Gallatin County | home | W | 65–38 | 13-5 | ||
| Fri, Feb 9, 2001 | Bullitt East | away | W | 61–58 | 14-5 | ||
| Tue, Feb 13, 2001 | Owen County | home | L | 38–55 | 14-6 | ||
| Thu, Feb 15, 2001 | Jeffersontown | home | W | 42–40 | 15-6 | ||
| Fri, Feb 16, 2001 | Trimble County | away | L | 57–67 | 15-7 | ||
| Tue, Feb 20, 2001 | Williamstown | home | W | 50–48 | 16-7 | ||
| Fri, Feb 23, 2001 | Walton-Verona | home | L | 51–60 | 16-8 | ||
| Thu, Mar 1, 2001 | Trimble County | away | L | 59–70 | 16-9 | 2001 31st District Girls Basketball Tournament |