Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Oldham County | away | L | 48–69 | 0-1 | ||
| Mon, Dec 4, 2000 | Central Hardin | home | L | 44–51 | 0-2 | ||
| Thu, Dec 7, 2000 | — | at floyd central, in | L | 47– | 0-3 | ||
| Fri, Dec 8, 2000 | North Bullitt | home | W | 42–28 | 1-3 | ||
| Tue, Dec 12, 2000 | Elizabethtown | away | W | 51–38 | 2-3 | ||
| Fri, Dec 15, 2000 | Bullitt Central | away | L | 40–46 | 2-4 | ||
| Wed, Dec 20, 2000 | Bardstown | home | W | 56–50 | 3-4 | ||
| Wed, Dec 27, 2000 | Paducah Tilghman | at daviess county | W | 78–42 | 4-4 | Lady Panther Invitational | |
| Thu, Dec 28, 2000 | North Laurel | at daviess county | W | 59–57 | 5-4 | Lady Panther Invitational (overtime) | |
| Tue, Jan 2, 2001 | Daviess County | away | L | 46–54 | 5-5 | Lady Panther Invitational (championship) | |
| Tue, Jan 9, 2001 | North Hardin | home | L | 41–44 | 5-6 | ||
| Thu, Jan 11, 2001 | Breckinridge County | home | W | 48–33 | 6-6 | ||
| Sat, Jan 13, 2001 | Bullitt East | home | W | 65–43 | 7-6 | ||
| Mon, Jan 15, 2001 | Grayson County | away | W | 50–41 | 8-6 | ||
| Thu, Jan 18, 2001 | Elizabethtown | home | L | 38–57 | 8-7 | ||
| Tue, Jan 23, 2001 | Hancock County | away | W | 59–32 | 9-7 | ||
| Thu, Jan 25, 2001 | LaRue County | home | W | 45–24 | 10-7 | ||
| Tue, Jan 30, 2001 | Central Hardin | away | L | 40–54 | 10-8 | ||
| Fri, Feb 2, 2001 | Fort Knox | home | W | 60–50 | 11-8 | ||
| Tue, Feb 6, 2001 | North Hardin | away | L | 41–42 | 11-9 | ||
| Fri, Feb 9, 2001 | Nelson County | home | W | 51–37 | 12-9 | ||
| Tue, Feb 13, 2001 | Fort Knox | away | L | 41–59 | 12-10 | ||
| Thu, Feb 15, 2001 | Fern Creek | away | W | 51–39 | 13-10 | ||
| Fri, Feb 23, 2001 | Southern | away | W | 67–37 | 14-10 | ||
| Tue, Feb 27, 2001 | North Hardin | away | W | 41–38 | 15-10 | 2001 17th District Girls Basketball Tournament | |
| Thu, Mar 1, 2001 | Central Hardin | at north hardin | W | 56–50 | 16-10 | 2001 17th District Girls Basketball Tournament | |
| Sat, Mar 3, 2001 | Elizabethtown | at north hardin | L | 46–59 | 16-11 | 2001 17th District Girls Basketball Tournament | |
| Thu, Mar 8, 2001 | Hart County | at green county | L | 38–56 | 16-12 | 2001 5th Region Girls Basketball Tournament |