Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 28, 2000 | Presentation | home | L | 27–87 | 0-1 | ||
| Thu, Nov 30, 2000 | Holy Rosary | at central | L | 44–77 | 0-2 | Jacketmania Tournament | |
| Sat, Dec 2, 2000 | Iroquois | at central | W | 78–50 | 1-2 | Jacketmania Tournament | |
| Tue, Dec 5, 2000 | Male | home | L | 41–68 | 1-3 | ||
| Fri, Dec 8, 2000 | Assumption | home | L | 39–62 | 1-4 | ||
| Tue, Dec 12, 2000 | DuPont Manual | away | L | 39–78 | 1-5 | ||
| Sat, Dec 16, 2000 | — | home | L | 50– | 1-6 | ||
| Tue, Dec 19, 2000 | Whitesburg | at berea college | L | 42–54 | 1-7 | Berea Holiday Classic | |
| Wed, Dec 20, 2000 | Evarts | at berea college | L | 32–45 | 1-8 | Berea Holiday Classic | |
| Thu, Dec 21, 2000 | Grant County | at berea college | W | 45–39 | 2-8 | Berea Holiday Classic | |
| Fri, Dec 22, 2000 | Western Hills | at berea college | L | 39–57 | 2-9 | Berea Holiday Classic | |
| Tue, Dec 26, 2000 | Doss | home | L | 46–47 | 2-10 | South Louisville Tournament (championship) | |
| Tue, Dec 26, 2000 | Western | home | W | 50–31 | 3-10 | South Louisville Tournament | |
| Tue, Jan 2, 2001 | Waggener | home | W | 68–37 | 4-10 | ||
| Fri, Jan 5, 2001 | Jeffersontown | home | L | 43–58 | 4-11 | ||
| Sat, Jan 6, 2001 | South Central (Union Mill), IN | at south central, in | L | 52–56 | 4-12 | ||
| Mon, Jan 8, 2001 | Nelson County | away | L | 51–73 | 4-13 | ||
| Tue, Jan 9, 2001 | Western | away | |||||
| Thu, Jan 11, 2001 | Whitefield Academy | home | W | 45–30 | 5-13 | ||
| Tue, Jan 16, 2001 | Seneca | home | W | 60–57 | 6-13 | ||
| Fri, Jan 19, 2001 | Moore | home | L | 34–77 | 6-14 | ||
| Mon, Jan 22, 2001 | Bardstown | home | L | 43–64 | 6-15 | ||
| Tue, Jan 30, 2001 | Mercy Academy | home | |||||
| Fri, Feb 2, 2001 | Eastern | home | L | 52–67 | 6-16 | ||
| Tue, Feb 6, 2001 | Atherton | home | W | 56–50 | 7-16 | ||
| Fri, Feb 9, 2001 | Ballard | away | L | 55–57 | 7-17 | ||
| Tue, Feb 13, 2001 | Butler | away | W | 57–55 | 8-17 | ||
| Thu, Feb 15, 2001 | Meade County | home | L | 39–51 | 8-18 | ||
| Fri, Feb 16, 2001 | Central | away | L | 43–57 | 8-19 | ||
| Thu, Mar 1, 2001 | Jeffersontown | at highview baptist | W | 35–34 | 9-19 | 2001 27th District Girls Basketball Tournament | |
| Sat, Mar 3, 2001 | Moore | at highview baptist | L | 42–76 | 9-20 | 2001 27th District Girls Basketball Tournament | |
| Wed, Mar 7, 2001 | Sacred Heart | away | L | 26–65 | 9-21 | 2001 7th Region Girls Basketball Tournament |