Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Dec 5, 2000 | Holy Rosary | away | W | 63–47 | 1-0 | ||
| Fri, Dec 8, 2000 | Pleasure Ridge Park | away | W | 79–55 | 2-0 | ||
| Tue, Dec 12, 2000 | Central | away | W | 63–54 | 3-0 | ||
| Wed, Dec 20, 2000 | Christian Academy-Louisville | at male | W | 65–60 | 4-0 | Male Holiday Classic | |
| Thu, Dec 21, 2000 | Nelson County | at male | W | 74–60 | 5-0 | Male Holiday Classic | |
| Fri, Dec 22, 2000 | Shelby County | at male | L | 52–67 | 5-1 | Male Holiday Classic | |
| Sat, Dec 23, 2000 | Assumption | at male | L | 53–54 | 5-2 | Male Holiday Classic | |
| Wed, Dec 27, 2000 | Nease, FL | at ft. myers, fl | W | 70–37 | 6-2 | City of Palms Tournament | |
| Tue, Jan 2, 2001 | Shawnee | home | (cancelled) | ||||
| Thu, Jan 4, 2001 | Holy Cross (Louisville) | away | |||||
| Fri, Jan 5, 2001 | Presentation | home | L | 56–62 | 6-3 | ||
| Thu, Jan 11, 2001 | Holy Cross (Louisville) | away | W | 61–59 | 7-3 | ||
| Tue, Jan 16, 2001 | Valley | home | W | 77–43 | 8-3 | ||
| Fri, Jan 19, 2001 | Iroquois | home | W | 94–37 | 9-3 | ||
| Sat, Jan 20, 2001 | Bishop Brossart | at trinity (louisville) | L | 52–61 | 9-4 | Kentucky Preps Plus Classic | |
| Tue, Jan 23, 2001 | Marion County | at louisville gardens | W | 58–34 | 10-4 | Louisville Invitational Tournament | |
| Wed, Jan 24, 2001 | Sacred Heart | at louisville gardens | L | 52–57 | 10-5 | Louisville Invitational Tournament | |
| Tue, Jan 30, 2001 | Southern | away | W | 70–31 | 11-5 | ||
| Fri, Feb 2, 2001 | Fairdale | away | W | 71–23 | 12-5 | ||
| Tue, Feb 6, 2001 | Doss | away | W | 69–44 | 13-5 | ||
| Wed, Feb 7, 2001 | DuPont Manual | away | |||||
| Fri, Feb 9, 2001 | Western | away | W | 57–27 | 14-5 | ||
| Mon, Feb 12, 2001 | Mercy Academy | at mercy | W | 65–64 | 15-5 | ||
| Tue, Feb 13, 2001 | Fern Creek | home | L | 55–57 | 15-6 | ||
| Thu, Feb 15, 2001 | Shelby County | home | L | 46–61 | 15-7 | ||
| Fri, Feb 16, 2001 | Male | home | L | 63–71 | 15-8 | ||
| Fri, Feb 23, 2001 | Jeffersontown | away | W | 58–44 | 16-8 | ||
| Tue, Feb 27, 2001 | Western | at pleasure ridge park | W | 62–24 | 17-8 | 2001 22nd District Girls Basketball Tournament | |
| Fri, Mar 2, 2001 | Holy Cross (Louisville) | at pleasure ridge park | W | 49–47 | 18-8 | 2001 22nd District Girls Basketball Tournament | |
| Wed, Mar 7, 2001 | Valley | home | W | 46–20 | 19-8 | 2001 6th Region Girls Basketball Tournament | |
| Fri, Mar 9, 2001 | Presentation | at louisville gardens | L | 60–66 | 19-9 | 2001 6th Region Girls Basketball Tournament |