Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Harlan | away | L | 50–54 | 0-1 | ||
| Tue, Nov 28, 2000 | Middlesboro | at harlan | L | 71–77 | 0-2 | Harlan County Round Robin | |
| Thu, Nov 30, 2000 | Cumberland | at harlan | L | 46–49 | 0-3 | Harlan County Round Robin | |
| Tue, Dec 5, 2000 | Pineville | away | W | 78–30 | 1-3 | ||
| Thu, Dec 7, 2000 | Lynn Camp | away | W | 53–35 | 2-3 | ||
| Sat, Dec 9, 2000 | Rockcastle County | home | L | 47–51 | 2-4 | ||
| Mon, Dec 11, 2000 | Cawood | home | L | 59–61 | 2-5 | ||
| Thu, Dec 14, 2000 | Cumberland | home | W | 52–39 | 3-5 | ||
| Tue, Dec 19, 2000 | Pulaski County | at berea college | L | 26–53 | 3-6 | Berea Holiday Classic | |
| Wed, Dec 20, 2000 | Fern Creek | at berea college | W | 45–32 | 4-6 | Berea Holiday Classic | |
| Thu, Dec 21, 2000 | Todd County Central | at berea college | L | 39–43 | 4-7 | Berea Holiday Classic | |
| Fri, Dec 22, 2000 | Casey County | at berea college | L | 48–62 | 4-8 | Berea Holiday Classic | |
| Tue, Jan 2, 2001 | Harlan | home | L | 41–45 | 4-9 | ||
| Thu, Jan 4, 2001 | Cumberland | away | L | 38–50 | 4-10 | ||
| Tue, Jan 9, 2001 | Barbourville | home | W | 44–17 | 5-10 | 13th Region All A Classic (2nd round) | |
| Thu, Jan 11, 2001 | Jackson County | at middlesboro | L | 44–66 | 5-11 | 13th Region All A Classic (semifinal) | |
| Mon, Jan 15, 2001 | Clay County | away | L | 42–44 | 5-12 | ||
| Thu, Jan 18, 2001 | Corbin | away | W | 46–45 | 6-12 | ||
| Mon, Jan 22, 2001 | Middlesboro | away | L | 43–57 | 6-13 | ||
| Thu, Jan 25, 2001 | Cawood | away | L | 40–67 | 6-14 | ||
| Mon, Jan 29, 2001 | Harlan | away | W | 44–36 | 7-14 | ||
| Thu, Feb 1, 2001 | Bell County | away | L | 41–48 | 7-15 | ||
| Mon, Feb 5, 2001 | Middlesboro | home | W | 54–49 | 8-15 | ||
| Tue, Feb 13, 2001 | Pineville | home | W | 77–36 | 9-15 | ||
| Thu, Feb 15, 2001 | Knox Central | home | W | 52–39 | 10-15 | ||
| Mon, Feb 19, 2001 | Whitley County | home | L | 37–45 | 10-16 | ||
| Wed, Feb 28, 2001 | Cawood | at harlan | L | 38–60 | 10-17 | 2001 52nd District Girls Basketball Tournament |