Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Pulaski County | home | L | 40–44 | 0-1 | ||
| Thu, Dec 7, 2000 | Whitley County | away | W | 49–46 | 1-1 | ||
| Sat, Dec 9, 2000 | Bourbon County | at garrard county | L | 41–46 | 1-2 | Three Bank Classic | |
| Mon, Dec 11, 2000 | Knox Central | home | W | 60–40 | 2-2 | ||
| Thu, Dec 14, 2000 | Bell County | away | W | 60–59 | 3-2 | ||
| Wed, Dec 20, 2000 | DuPont Manual | at lexington catholic | L | 45–60 | 3-3 | 5/3 Bank Prime Time Classic | |
| Thu, Dec 21, 2000 | Lincoln County | at lexington catholic | L | 49–54 | 3-4 | 5/3 Bank Prime Time Classic | |
| Fri, Dec 22, 2000 | Montgomery County | at lexington catholic | L | 37–48 | 3-5 | 5/3 Bank Prime Time Classic | |
| Sat, Dec 23, 2000 | Sheldon Clark | at lexington catholic | W | 58–50 | 4-5 | 5/3 Bank Prime Time Classic | |
| Thu, Dec 28, 2000 | Anderson County, TN | at rockcastle county | L | 34–45 | 4-6 | Lady Rockets Holiday Hoopla | |
| Fri, Dec 29, 2000 | Casey County | at rockcastle county | L | 44–55 | 4-7 | Lady Rockets Holiday Hoopla | |
| Sat, Dec 30, 2000 | Montgomery County | at rockcastle county | L | 53–58 | 4-8 | Lady Rockets Holiday Hoopla | |
| Mon, Jan 8, 2001 | Cawood | away | L | 42–68 | 4-9 | ||
| Sat, Jan 13, 2001 | Rockcastle County | home | L | 51–56 | 4-10 | ||
| Tue, Jan 16, 2001 | Knox Central | away | W | 62–50 | 5-10 | ||
| Thu, Jan 18, 2001 | Evarts | home | L | 45–46 | 5-11 | ||
| Mon, Jan 22, 2001 | McCreary Central | home | W | 47–44 | 6-11 | (overtime) | |
| Fri, Jan 26, 2001 | Middlesboro | away | W | 63–45 | 7-11 | ||
| Mon, Jan 29, 2001 | Clay County | away | L | 33–52 | 7-12 | ||
| Tue, Jan 30, 2001 | Pineville | home | W | 77–22 | 8-12 | ||
| Thu, Feb 1, 2001 | Cumberland | away | W | 48–47 | 9-12 | ||
| Tue, Feb 6, 2001 | Williamsburg | home | W | 68–37 | 10-12 | ||
| Thu, Feb 8, 2001 | Lexington Catholic | away | L | 58–77 | 10-13 | ||
| Mon, Feb 12, 2001 | McCreary Central | away | L | 24–54 | 10-14 | ||
| Thu, Feb 15, 2001 | Casey County | home | W | 58–56 | 11-14 | ||
| Mon, Feb 19, 2001 | North Laurel | home | W | 52–50 | 12-14 | ||
| Fri, Feb 23, 2001 | Harlan | away | W | 55–52 | 13-14 | ||
| Tue, Feb 27, 2001 | Barbourville | at knox central | W | 78–26 | 14-14 | 2001 50th District Girls Basketball Tournament | |
| Thu, Mar 1, 2001 | Whitley County | at knox central | L | 48–61 | 14-15 | 2001 50th District Girls Basketball Tournament |