Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Thu, Nov 30, 2000 | Somerset | at perry county central | L | 46–59 | 0-1 | Queen of the Mountains Tip-Off Classic | |
| Mon, Dec 4, 2000 | Knox Central | away | L | 40–53 | 0-2 | ||
| Thu, Dec 7, 2000 | Cumberland | away | W | 54–49 | 1-2 | ||
| Mon, Dec 11, 2000 | Evarts | away | W | 61–59 | 2-2 | ||
| Thu, Dec 14, 2000 | Breathitt County | home | W | 61–43 | 3-2 | ||
| Tue, Dec 19, 2000 | Gainesville, FL | at berea college | W | 61–35 | 4-2 | Berea Holiday Classic | |
| Wed, Dec 20, 2000 | Bourbon County | at berea college | W | 60–45 | 5-2 | Berea Holiday Classic | |
| Thu, Dec 21, 2000 | Garrard County | at berea college | L | 43–63 | 5-3 | Berea Holiday Classic | |
| Fri, Dec 22, 2000 | Paris | at berea college | L | 48–50 | 5-4 | Berea Holiday Classic | |
| Thu, Jan 4, 2001 | Harlan | away | L | 56–64 | 5-5 | ||
| Sat, Jan 6, 2001 | Jackson County | home | L | 57–104 | 5-6 | ||
| Mon, Jan 8, 2001 | Corbin | home | W | 68–42 | 6-6 | ||
| Mon, Jan 15, 2001 | Bell County | away | W | 81–56 | 7-6 | ||
| Thu, Jan 18, 2001 | Cumberland | home | L | 56–63 | 7-7 | ||
| Mon, Jan 22, 2001 | Knox Central | home | W | 66–52 | 8-7 | ||
| Thu, Jan 25, 2001 | Evarts | home | W | 67–40 | 9-7 | ||
| Mon, Jan 29, 2001 | Whitley County | home | L | 75–79 | 9-8 | (overtime) | |
| Thu, Feb 1, 2001 | Harlan | home | W | 68–64 | 10-8 | ||
| Tue, Feb 6, 2001 | Pineville | home | W | 83–23 | 11-8 | ||
| Thu, Feb 8, 2001 | Whitesburg | home | W | 80–65 | 12-8 | ||
| Fri, Feb 9, 2001 | Madison Southern | away | W | 60–44 | 13-8 | ||
| Sat, Feb 10, 2001 | Berea | away | L | 67–69 | 13-9 | ||
| Fri, Feb 16, 2001 | Middlesboro | home | W | 45–35 | 14-9 | ||
| Thu, Feb 22, 2001 | Clay County | home | L | 46–61 | 14-10 | ||
| Wed, Feb 28, 2001 | Evarts | at harlan | W | 60–38 | 15-10 | 2001 52nd District Girls Basketball Tournament | |
| Fri, Mar 2, 2001 | Harlan | away | W | 56–49 | 16-10 | 2001 52nd District Girls Basketball Tournament | |
| Thu, Mar 8, 2001 | Knox Central | home | W | 75–62 | 17-10 | 2001 13th Region Girls Basketball Tournament | |
| Mon, Mar 12, 2001 | Jackson County | home | L | 46–88 | 17-11 | 2001 13th Region Girls Basketball Tournament |