Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Lee County | away | W | 68–49 | 1-0 | ||
| Thu, Nov 30, 2000 | Clay County | at perry country central | L | 40–51 | 1-1 | Queen of the Mountains Tip-Off Classic | |
| Thu, Dec 7, 2000 | Fleming-Neon | home | W | 68–45 | 2-1 | ||
| Mon, Dec 11, 2000 | Letcher | home | W | 82–49 | 3-1 | ||
| Thu, Dec 14, 2000 | Prestonsburg | away | L | 49–57 | 3-2 | ||
| Tue, Dec 19, 2000 | Fern Creek | at berea college | W | 54–42 | 4-2 | Berea Holiday Classic | |
| Wed, Dec 20, 2000 | Pulaski County | at berea college | L | 41–63 | 4-3 | Berea Holiday Classic | |
| Thu, Dec 21, 2000 | Whitley County | at berea college | L | 54–65 | 4-4 | Berea Holiday Classic | |
| Thu, Jan 4, 2001 | Jenkins | home | W | 75–64 | 5-4 | ||
| Mon, Jan 15, 2001 | Pikeville | away | L | 53–61 | 5-5 | ||
| Mon, Jan 22, 2001 | Fleming-Neon | away | W | 67–55 | 6-5 | ||
| Thu, Jan 25, 2001 | Knott County Central | home | W | 74–53 | 7-5 | ||
| Fri, Jan 26, 2001 | Leslie County | away | L | 49–66 | 7-6 | ||
| Mon, Jan 29, 2001 | Jenkins | away | W | 79–70 | 8-6 | ||
| Thu, Feb 1, 2001 | Breathitt County | away | L | 39–57 | 8-7 | ||
| Mon, Feb 5, 2001 | Pike County Central | away | W | 84–62 | 9-7 | ||
| Wed, Feb 7, 2001 | June Buchanan | home | W | 57–40 | 10-7 | ||
| Thu, Feb 8, 2001 | Cawood | away | L | 65–80 | 10-8 | ||
| Sat, Feb 10, 2001 | Letcher | away | W | 68–47 | 11-8 | ||
| Mon, Feb 19, 2001 | Leslie County | home | L | 60–63 | 11-9 | ||
| Thu, Feb 22, 2001 | Allen Central | home | W | 87–55 | 12-9 | ||
| Tue, Feb 27, 2001 | Letcher | at fleming-neon | W | 78–50 | 13-9 | 2001 53rd District Girls Basketball Tournament | |
| Sat, Mar 3, 2001 | Jenkins | at fleming-neon | L | 70–76 | 13-10 | 2001 53rd District Girls Basketball Tournament | |
| Thu, Mar 8, 2001 | Perry County Central | at powell county | L | 66–77 | 13-11 | 2001 14th Region Girls Basketball Tournament |