Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Thu, Nov 30, 2000 | Bell County | home | W | 45–39 | 1-0 | ||
| Mon, Dec 4, 2000 | South Laurel | home | W | 56–49 | 2-0 | ||
| Thu, Dec 7, 2000 | Corbin | home | L | 46–49 | 2-1 | ||
| Mon, Dec 11, 2000 | Jellico, TN | home | W | 75–29 | 3-1 | ||
| Tue, Dec 12, 2000 | Williamsburg | away | W | 76–23 | 4-1 | ||
| Thu, Dec 14, 2000 | Southwestern | home | W | 58–57 | 5-1 | ||
| Tue, Dec 19, 2000 | Grant County | at berea college | W | 69–22 | 6-1 | Berea Holiday Classic | |
| Wed, Dec 20, 2000 | Marietta, OH | at berea college | L | 59–60 | 6-2 | Berea Holiday Classic | |
| Thu, Dec 21, 2000 | Whitesburg | at berea college | W | 65–54 | 7-2 | Berea Holiday Classic | |
| Fri, Dec 22, 2000 | Breathitt County | at berea college | L | 53–62 | 7-3 | Berea Holiday Classic | |
| Thu, Jan 4, 2001 | Lynn Camp | away | W | 54–27 | 8-3 | ||
| Sat, Jan 6, 2001 | Fleming County | at ashland blazer | W | 56–32 | 9-3 | Ashland Kittens Invitational Tournament | |
| Thu, Jan 11, 2001 | Rockcastle County | away | L | 60–63 | 9-4 | ||
| Sat, Jan 13, 2001 | Ashland Blazer | away | L | 45–49 | 9-5 | Ashland Kittens Invitational Tournament | |
| Thu, Jan 18, 2001 | Barbourville | home | W | 71–23 | 10-5 | ||
| Mon, Jan 22, 2001 | Clay County | away | L | 34–59 | 10-6 | ||
| Mon, Jan 29, 2001 | Cawood | away | W | 79–75 | 11-6 | (overtime) | |
| Thu, Feb 1, 2001 | North Laurel | home | W | 57–54 | 12-6 | ||
| Mon, Feb 5, 2001 | Jellico, TN | away | W | 67–35 | 13-6 | ||
| Tue, Feb 6, 2001 | Knox Central | home | W | 64–57 | 14-6 | ||
| Tue, Feb 13, 2001 | Middlesboro | home | W | 78–54 | 15-6 | ||
| Fri, Feb 16, 2001 | Bell County | away | W | 66–45 | 16-6 | ||
| Mon, Feb 19, 2001 | Evarts | away | W | 45–37 | 17-6 | ||
| Thu, Mar 1, 2001 | Corbin | at knox central | W | 61–48 | 18-6 | 2001 50th District Girls Basketball Tournament | |
| Fri, Mar 2, 2001 | Knox Central | away | W | 52–50 | 19-6 | 2001 50th District Girls Basketball Tournament | |
| Wed, Mar 7, 2001 | Harlan | at cawood | W | 69–58 | 20-6 | 2001 13th Region Girls Basketball Tournament | |
| Mon, Mar 12, 2001 | Clay County | at cawood | W | 56–49 | 21-6 | 2001 13th Region Girls Basketball Tournament | |
| Tue, Mar 13, 2001 | Jackson County | at cawood | L | 57–89 | 21-7 | 2001 13th Region Girls Basketball Tournament |