Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Sat, Dec 2, 2000 | Marion County | home | W | 53–41 | 1-0 | Eastern Extravaganza | |
| Tue, Dec 5, 2000 | DuPont Manual | home | L | 39–58 | 1-1 | ||
| Fri, Dec 8, 2000 | Waggener | away | W | 77–26 | 2-1 | ||
| Wed, Dec 13, 2000 | Oldham County | away | (cancelled) | ||||
| Fri, Dec 15, 2000 | Christian Academy-Louisville | home | W | 60–55 | 3-1 | ||
| Wed, Dec 20, 2000 | Shelby County | at male | L | 41–61 | 3-2 | Male Holiday Classic | |
| Thu, Dec 21, 2000 | Southern | at male | W | 57–45 | 4-2 | Male Holiday Classic | |
| Fri, Dec 22, 2000 | Christian Academy-Louisville | at male | L | 45–59 | 4-3 | Male Holiday Classic | |
| Wed, Jan 3, 2001 | Jeffersontown | home | W | 61–55 | 5-3 | ||
| Fri, Jan 5, 2001 | Ballard | home | W | 57–54 | 6-3 | (overtime) | |
| Thu, Jan 11, 2001 | Sacred Heart | home | L | 46–65 | 6-4 | ||
| Tue, Jan 16, 2001 | Mercy Academy | at mercy | L | 54–90 | 6-5 | ||
| Fri, Jan 19, 2001 | Atherton | away | W | 57–43 | 7-5 | ||
| Thu, Jan 25, 2001 | Pleasure Ridge Park | away | L | 62–66 | 7-6 | ||
| Tue, Jan 30, 2001 | Moore | away | L | 52–70 | 7-7 | ||
| Fri, Feb 2, 2001 | Fern Creek | away | W | 67–52 | 8-7 | ||
| Tue, Feb 6, 2001 | Male | away | L | 56–64 | 8-8 | ||
| Fri, Feb 9, 2001 | Seneca | away | W | 90–48 | 9-8 | ||
| Tue, Feb 13, 2001 | Assumption | away | L | 50–64 | 9-9 | ||
| Thu, Feb 15, 2001 | Holy Cross (Louisville) | home | L | 49–54 | 9-10 | ||
| Tue, Feb 20, 2001 | South Oldham | away | W | 72–50 | 10-10 | ||
| Thu, Feb 22, 2001 | Shelby County | away | L | 64–80 | 10-11 | ||
| Thu, Mar 1, 2001 | Christian Academy-Louisville | at chrisitan academy-louisville | L | 53–57 | 10-12 | 2001 28th District Girls Basketball Tournament |