Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Apollo | home | W | 59–44 | 1-0 | ||
| Thu, Nov 30, 2000 | Ohio County | away | W | 62–51 | 2-0 | ||
| Mon, Dec 4, 2000 | Breckinridge County | away | W | 53–44 | 3-0 | ||
| Thu, Dec 7, 2000 | Hopkins County Central | home | W | 76–52 | 4-0 | ||
| Mon, Dec 11, 2000 | Muhlenberg North | away | L | 69–78 | 4-1 | ||
| Thu, Dec 14, 2000 | McLean County | away | W | 68–37 | 5-1 | ||
| Wed, Dec 20, 2000 | Holy Rosary | at male | W | 50–34 | 6-1 | Male Holiday Classic | |
| Thu, Dec 21, 2000 | Assumption | at male | L | 40–63 | 6-2 | Male Holiday Classic | |
| Fri, Dec 22, 2000 | North Hardin | at male | W | 64–51 | 7-2 | Male Holiday Classic | |
| Sat, Dec 23, 2000 | Nelson County | at male | W | 75–64 | 8-2 | Male Holiday Classic | |
| Thu, Dec 28, 2000 | Union County | away | L | 58–70 | 8-3 | State Farm Classic | |
| Sat, Dec 30, 2000 | Hopkins County Central | at union county | W | 51–46 | 9-3 | State Farm Classic | |
| Sat, Dec 30, 2000 | Australian Team | at union county | W | 55–54 | 10-3 | State Farm Classic (championship) | |
| Thu, Jan 4, 2001 | Warren East | away | L | 57–63 | 10-4 | ||
| Mon, Jan 8, 2001 | Butler County | away | L | 63–66 | 10-5 | ||
| Mon, Jan 15, 2001 | Henderson County | away | W | 66–57 | 11-5 | ||
| Thu, Jan 18, 2001 | Grayson County | home | W | 67–30 | 12-5 | ||
| Mon, Jan 22, 2001 | Elizabethtown | home | W | 57–55 | 13-5 | (overtime) | |
| Thu, Jan 25, 2001 | Webster County | home | W | 45–37 | 14-5 | ||
| Mon, Jan 29, 2001 | Muhlenberg North | home | L | 50–52 | 14-6 | ||
| Fri, Feb 2, 2001 | Madisonville-North Hopkins | away | L | 51–62 | 14-7 | ||
| Mon, Feb 5, 2001 | Hopkinsville | home | L | 44–66 | 14-8 | ||
| Tue, Feb 6, 2001 | Daviess County | away | W | 56–42 | 15-8 | ||
| Fri, Feb 9, 2001 | Logan County | away | W | 65–64 | 16-8 | ||
| Mon, Feb 12, 2001 | Owensboro | home | W | 72–55 | 17-8 | ||
| Thu, Feb 15, 2001 | Christian County | away | L | 54–77 | 17-9 | ||
| Mon, Feb 19, 2001 | Owensboro Catholic | away | W | 54–36 | 18-9 | ||
| Tue, Feb 20, 2001 | Hancock County | away | W | 59–22 | 19-9 | ||
| Thu, Mar 1, 2001 | Butler County | away | W | 62–51 | 20-9 | 2001 10th District Girls Basketball Tournament | |
| Sat, Mar 3, 2001 | Muhlenberg North | at butler county | L | 48–66 | 20-10 | 2001 10th District Girls Basketball Tournament | |
| Thu, Mar 8, 2001 | Owensboro Catholic | at hancock county | W | 59–31 | 21-10 | 2001 3rd Region Girls Basketball Tournament | |
| Mon, Mar 12, 2001 | Ohio County | at hancock county | L | 51–65 | 21-11 | 2001 3rd Region Girls Basketball Tournament |