Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 28, 2000 | Madisonville-North Hopkins | home | W | 50–45 | 1-0 | overtime | |
| Thu, Nov 30, 2000 | Caldwell County | away | L | 54–59 | 1-1 | ||
| Mon, Dec 4, 2000 | Webster County | away | L | 29–36 | 1-2 | ||
| Thu, Dec 7, 2000 | Hopkinsville | away | W | 40–39 | 2-2 | ||
| Mon, Dec 11, 2000 | Henderson County | away | L | 35–51 | 2-3 | ||
| Thu, Dec 28, 2000 | Muhlenberg South | home | W | 70–58 | 3-3 | State Farm Classic | |
| Fri, Dec 29, 2000 | Australian Team | home | L | 45–60 | 3-4 | State Farm Classic | |
| Sat, Dec 30, 2000 | Holy Rosary | home | W | 71–36 | 4-4 | State Farm Classic | |
| Sat, Jan 6, 2001 | Muhlenberg North | home | L | 40–52 | 4-5 | ||
| Mon, Jan 8, 2001 | Hopkins County Central | home | W | 86–49 | 5-5 | ||
| Thu, Jan 11, 2001 | Webster County | home | L | 50–53 | 5-6 | ||
| Sat, Jan 13, 2001 | Apollo | home | W | 65–49 | 6-6 | ||
| Mon, Jan 15, 2001 | Butler County | home | W | 57–25 | 7-6 | ||
| Tue, Jan 16, 2001 | Crittenden County | away | W | 65–30 | 8-6 | ||
| Mon, Jan 22, 2001 | Henderson County | home | L | 42–53 | 8-7 | ||
| Fri, Jan 26, 2001 | Christian County | home | W | 71–64 | 9-7 | ||
| Fri, Feb 2, 2001 | Hopkins County Central | away | W | 70–28 | 10-7 | ||
| Thu, Feb 8, 2001 | Hancock County | away | W | 83–35 | 11-7 | ||
| Sat, Feb 10, 2001 | Livingston Central | away | W | 70–26 | 12-7 | ||
| Sat, Feb 17, 2001 | Caldwell County | home | W | 71–48 | 13-7 | ||
| Tue, Feb 20, 2001 | Owensboro | away | W | 66–44 | 14-7 | ||
| Thu, Feb 22, 2001 | Lyon County | home | W | 73–42 | 15-7 | ||
| Tue, Feb 27, 2001 | Henderson County | at webster county | L | 48–59 | 15-8 | 2001 6th District Girls Basketball Tournament | |
| Thu, Mar 1, 2001 | Webster County | away | L | 35–44 | 15-9 | 2001 6th District Girls Basketball Tournament |