Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Trigg County | away | W | 67–39 | 1-0 | ||
| Fri, Dec 1, 2000 | Fort Campbell | away | W | 54–39 | 2-0 | ||
| Mon, Dec 4, 2000 | Muhlenberg North | away | L | 57–75 | 2-1 | ||
| Thu, Dec 7, 2000 | Union County | home | L | 39–40 | 2-2 | ||
| Mon, Dec 11, 2000 | Webster County | away | L | 41–59 | 2-3 | ||
| Thu, Dec 14, 2000 | Christian County | home | L | 80–101 | 2-4 | ||
| Wed, Dec 20, 2000 | Notre Dame, MO | at semo university | L | 38–57 | 2-5 | Healthsouth Holiday Classic | |
| Thu, Dec 21, 2000 | Massac County, IL | at semo university | L | 62–63 | 2-6 | Healthsouth Holiday Classic | |
| Fri, Dec 22, 2000 | Perryville, MO | at semo university | L | 63–67 | 2-7 | Healthsouth Holiday Classic | |
| Thu, Dec 28, 2000 | Heath | at murray | W | 53–52 | 3-7 | Lady Tiger Classic | |
| Tue, Jan 2, 2001 | Livingston Central | home | W | 52–23 | 4-7 | ||
| Mon, Jan 8, 2001 | Russellville | away | W | 73–66 | 5-7 | ||
| Thu, Jan 11, 2001 | Henderson County | away | L | 35–70 | 5-8 | ||
| Fri, Jan 12, 2001 | Christian County | away | L | 66–73 | 5-9 | ||
| Mon, Jan 15, 2001 | Caldwell County | home | L | 49–62 | 5-10 | ||
| Tue, Jan 16, 2001 | Madisonville-North Hopkins | home | L | 46–80 | 5-11 | ||
| Sat, Jan 20, 2001 | Calloway County | home | W | 60–52 | 6-11 | ||
| Thu, Jan 25, 2001 | Hopkins County Central | home | L | 53–62 | 6-12 | ||
| Fri, Feb 2, 2001 | Fort Campbell | home | W | 61–53 | 7-12 | ||
| Sat, Feb 3, 2001 | Todd County Central | home | L | 46–75 | 7-13 | ||
| Mon, Feb 5, 2001 | Muhlenberg South | away | W | 66–44 | 8-13 | ||
| Thu, Feb 8, 2001 | Crittenden County | away | W | 59–49 | 9-13 | ||
| Thu, Feb 15, 2001 | Paducah Tilghman | away | W | 78–54 | 10-13 | ||
| Tue, Feb 20, 2001 | Marshall County | home | L | 53–77 | 10-14 | ||
| Thu, Feb 22, 2001 | Dawson Springs | away | W | 65–59 | 11-14 | ||
| Mon, Feb 26, 2001 | Christian County | away | L | 66–78 | 11-15 | 2001 8th District Girls Basketball Tournament | |
| Tue, Feb 27, 2001 | Fort Campbell | at christian county | W | 54–34 | 12-15 | 2001 8th District Girls Basketball Tournament | |
| Wed, Mar 7, 2001 | Madisonville-North Hopkins | away | L | 55–69 | 12-16 | 2001 2nd Region Girls Basketball Tournament |