Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Monroe County | away | W | 56–53 | 1-0 | ||
| Thu, Nov 30, 2000 | Elizabethtown | home | W | 66–59 | 2-0 | ||
| Sat, Dec 2, 2000 | Butler County | away | W | 74–72 | 3-0 | (overtime) | |
| Tue, Dec 5, 2000 | Warren Central | away | W | 70–44 | 4-0 | ||
| Thu, Dec 7, 2000 | Russellville | away | W | 73–54 | 5-0 | ||
| Tue, Dec 12, 2000 | Greenwood | away | W | 58–57 | 6-0 | ||
| Tue, Dec 19, 2000 | Taylor County | at berea college | W | 67–48 | 7-0 | Berea Holiday Classic | |
| Wed, Dec 20, 2000 | Garrard County | at berea college | L | 59–61 | 7-1 | Berea Holiday Classic | |
| Thu, Dec 21, 2000 | Bourbon County | at berea college | W | 61–37 | 8-1 | Berea Holiday Classic | |
| Fri, Dec 22, 2000 | Johnson Central | at berea college | L | 55–57 | 8-2 | Berea Holiday Classic | |
| Wed, Dec 27, 2000 | Henderson County | at allen county-scottsville | L | 38–62 | 8-3 | Lady Invitational of the South | |
| Thu, Dec 28, 2000 | Prattville, AL | at allen county-scottsville | W | 72–37 | 9-3 | Lady Invitational of the South | |
| Fri, Dec 29, 2000 | Clinton County | at allen county-scottsville | L | 47–53 | 9-4 | Lady Invitational of the South | |
| Thu, Jan 4, 2001 | Muhlenberg South | home | W | 63–57 | 10-4 | ||
| Tue, Jan 9, 2001 | Bowling Green | home | L | 59–64 | 10-5 | ||
| Fri, Jan 12, 2001 | Allen County-Scottsville | home | L | 46–72 | 10-6 | ||
| Tue, Jan 16, 2001 | North Hardin | away | L | 54–56 | 10-7 | ||
| Thu, Jan 18, 2001 | Warren Central | home | W | 66–47 | 11-7 | ||
| Mon, Jan 22, 2001 | Ohio County | home | L | 68–75 | 11-8 | ||
| Thu, Jan 25, 2001 | Logan County | home | L | 80–84 | 11-9 | ||
| Sat, Jan 27, 2001 | Henderson County | away | L | 66–77 | 11-10 | ||
| Tue, Jan 30, 2001 | Greenwood | home | W | 57–52 | 12-10 | ||
| Fri, Feb 2, 2001 | Bowling Green | away | W | 62–59 | 13-10 | ||
| Fri, Feb 9, 2001 | Barren County | away | L | 60–64 | 13-11 | ||
| Thu, Feb 15, 2001 | Russellville | home | W | 62–52 | 14-11 | ||
| Mon, Feb 19, 2001 | Apollo | away | W | 60–56 | 15-11 | ||
| Tue, Feb 20, 2001 | Franklin-Simpson | away | L | 63–68 | 15-12 | (overtime) | |
| Tue, Feb 27, 2001 | Warren Central | at greenwood | L | 54–62 | 15-13 | 2001 14th District Girls Basketball Tournament |