Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Dayton | home | W | 77–20 | 1-0 | ||
| Mon, Dec 4, 2000 | Bishop Brossart | home | L | 49–57 | 1-1 | ||
| Thu, Dec 7, 2000 | Ludlow | away | W | 67–31 | 2-1 | ||
| Mon, Dec 11, 2000 | Bellevue | away | W | 74–31 | 3-1 | ||
| Mon, Dec 18, 2000 | Presentation | at central hardin | L | 52–68 | 3-2 | Republic Bank Invitational | |
| Tue, Dec 19, 2000 | Belfry | at central hardin | W | 68–67 | 4-2 | Republic Bank Classic | |
| Thu, Dec 21, 2000 | Scott | away | W | 56–48 | 5-2 | ||
| Wed, Dec 27, 2000 | Harrison County | at east carter | W | 59–50 | 6-2 | Queen of the Bluegrass | |
| Thu, Dec 28, 2000 | Assumption | at east carter | L | 48–59 | 6-3 | Queen of the Bluegrass | |
| Fri, Dec 29, 2000 | Boyd County | at east carter | L | 61–62 | 6-4 | Queen of the Bluegrass | |
| Wed, Jan 3, 2001 | Highlands | away | L | 35–46 | 6-5 | Northern Kentucky Classic | |
| Thu, Jan 4, 2001 | St. Patrick | at highlands | W | 55–39 | 7-5 | Northern Kentucky Classic | |
| Sat, Jan 6, 2001 | Australian Team | at bishop brossart | W | 59–57 | 8-5 | Northern Kentucky Classic | |
| Sat, Jan 6, 2001 | Shelby Valley | at bishop brossart | W | 80–69 | 9-5 | Northern Kentucky Classic | |
| Thu, Jan 11, 2001 | Villa Madonna | home | W | 57–49 | 10-5 | 9th Region All A Classic (2nd round) | |
| Fri, Jan 12, 2001 | Bellevue | home | W | 71–27 | 11-5 | 9th Region All A Classic (semifinal) | |
| Sat, Jan 13, 2001 | Newport Central Catholic | home | L | 47–60 | 11-6 | 9th Region All A Classic (championship) | |
| Mon, Jan 15, 2001 | Lloyd Memorial | home | W | 61–42 | 12-6 | ||
| Thu, Jan 18, 2001 | Highlands | away | W | 54–44 | 13-6 | ||
| Mon, Jan 29, 2001 | Boone County | away | L | 41–59 | 13-7 | ||
| Thu, Feb 1, 2001 | Ryle | home | W | 63–46 | 14-7 | ||
| Mon, Feb 5, 2001 | Conner | away | W | 55–41 | 15-7 | ||
| Thu, Feb 8, 2001 | Simon Kenton | home | W | 76–32 | 16-7 | ||
| Mon, Feb 12, 2001 | Holy Cross (Covington) | away | W | 54–52 | 17-7 | ||
| Thu, Feb 15, 2001 | Notre Dame | home | L | 69–73 | 17-8 | ||
| Mon, Feb 19, 2001 | St. Henry | home | W | 68–54 | 18-8 | ||
| Thu, Feb 22, 2001 | Holmes | away | L | 65–69 | 18-9 | ||
| Thu, Mar 1, 2001 | Newport Central Catholic | at bellevue | L | 54–82 | 18-10 | 2001 36th District Girls Basketball Tournament |