Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 29, 2021 | Whitefield Academy | away | L | 50–63 | 0-1 | ||
| Tue, Nov 30, 2021 | Doss | home | W | 56–8 | 1-1 | ||
| Fri, Dec 3, 2021 | Jeffersontown | away | W | 58–9 | 2-1 | ||
| Mon, Dec 6, 2021 | Holy Cross (Louisville) | away | W | 65–52 | 3-1 | ||
| Wed, Dec 8, 2021 | Presentation | away | W | 57–50 | 4-1 | ||
| Fri, Dec 10, 2021 | Valley | away | W | 67–14 | 5-1 | ||
| Mon, Dec 13, 2021 | Meade County | away | L | 42–66 | 5-2 | ||
| Sat, Dec 18, 2021 | West Carter | at berea | L | 51–64 | 5-3 | ||
| Sun, Dec 19, 2021 | Berea | away | L | 41–54 | 5-4 | Berea Holiday Classic | |
| Mon, Dec 20, 2021 | Raceland | at berea | L | 64–65 | 5-5 | ||
| Mon, Dec 27, 2021 | Danville | away | L | 33–73 | 5-6 | ||
| Tue, Dec 28, 2021 | Ballard | at danville | L | 41–50 | 5-7 | Lady Ads Tournament | |
| Wed, Dec 29, 2021 | Knott County Central | at danville | L | 45–50 | 5-8 | ||
| Wed, Jan 5, 2022 | DuPont Manual | home | L | 32–66 | 5-9 | ||
| Sat, Jan 8, 2022 | South Oldham | away | L | 60–81 | 5-10 | ||
| Mon, Jan 10, 2022 | Mercy Academy | home | L | 54–84 | 5-11 | ||
| Sat, Jan 15, 2022 | Oldham County | away | W | 66–38 | 6-11 | ||
| Tue, Jan 18, 2022 | Southern | home | W | 1–0 | 7-11 | COVID Cancelation - RPI per Policy | |
| Fri, Jan 21, 2022 | Nelson County | away | L | 49–67 | 7-12 | ||
| Mon, Jan 24, 2022 | North Bullitt | home | W | 56–45 | 8-12 | Republic Bank Louisville Invitational Tourn… | |
| Tue, Jan 25, 2022 | Mercy Academy | at valley | L | 40–60 | 8-13 | ||
| Sat, Jan 29, 2022 | Bowling Green | at various sites | L | 50–73 | 8-14 | Republic Bank Louisville Invitational Tourn… | |
| Tue, Feb 1, 2022 | Bullitt Central | away | W | 61–47 | 9-14 | ||
| Mon, Feb 7, 2022 | Fairdale | home | W | 84–23 | 10-14 | ||
| Tue, Feb 8, 2022 | Iroquois | away | W | 72–19 | 11-14 | ||
| Thu, Feb 10, 2022 | Butler | L | 40–51 | 11-15 | |||
| Sat, Feb 12, 2022 | Male | away | L | 39–62 | 11-16 | ||
| Tue, Feb 15, 2022 | Fern Creek | home | W | 85–50 | 12-16 | ||
| Thu, Feb 17, 2022 | Beth Haven | home | W | 75–27 | 13-16 | ||
| Fri, Feb 18, 2022 | Western | home | W | 56–3 | 14-16 | ||
| Tue, Feb 22, 2022 | Valley | away | W | 66–22 | 15-16 | 2022 21st District Girls Basketball Tournament | |
| Fri, Feb 25, 2022 | Holy Cross (Louisville) | at valley | W | 57–43 | 16-16 | 2022 21st District Girls Basketball Tournament | |
| Mon, Feb 28, 2022 | North Bullitt | home | W | 70–39 | 17-16 | 2022 6th Region Girls Basketball Tournament | |
| Thu, Mar 3, 2022 | Mercy Academy | at valley | L | 44–75 | 17-17 | 2022 6th Region Girls Basketball Tournament |