Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 29, 2021 | Highlands Latin | away | W | 43–36 | 1-0 | ||
| Tue, Nov 30, 2021 | Fairdale | away | W | 59–46 | 2-0 | ||
| Fri, Dec 3, 2021 | Pleasure Ridge Park | home | L | 9–58 | 2-1 | ||
| Tue, Dec 7, 2021 | Doss | away | W | 52–36 | 3-1 | ||
| Fri, Dec 10, 2021 | Whitefield Academy | home | L | 22–54 | 3-2 | ||
| Fri, Dec 17, 2021 | Seneca | at western | W | 46–36 | 4-2 | Western Girls Holiday Hoops Classic | |
| Sat, Dec 18, 2021 | Brown | at western | W | 40–15 | 5-2 | Western Girls Holiday Hoops Classic | |
| Sat, Dec 18, 2021 | Fairdale | at western | W | 39–27 | 6-2 | Western Girls Holiday Hoops Classic | |
| Sun, Dec 19, 2021 | Atherton | at western | W | 44–33 | 7-2 | Louisville Western Holiday Classic | |
| Thu, Jan 6, 2022 | Waggener | home | W | 24–19 | 8-2 | ||
| Tue, Jan 18, 2022 | Western | home | W | 51–16 | 9-2 | ||
| Fri, Jan 21, 2022 | Fern Creek | away | L | 49–56 | 9-3 | ||
| Tue, Jan 25, 2022 | Brown | home | W | 46–19 | 10-3 | ||
| Thu, Jan 27, 2022 | Southern | away | W | 55–29 | 11-3 | ||
| Mon, Jan 31, 2022 | Louisville Collegiate | home | W | 47–42 | 12-3 | (overtime) | |
| Tue, Feb 1, 2022 | Valley | away | W | 39–23 | 13-3 | ||
| Tue, Feb 8, 2022 | Moore | home | L | 19–45 | 13-4 | ||
| Fri, Feb 11, 2022 | Villa Madonna | at highlands latin | L | 22–39 | 13-5 | Louisville Valentines Classic | |
| Sat, Feb 12, 2022 | Beth Haven | at highlands latin | L | 28–47 | 13-6 | Louisville Valentines Classic | |
| Sat, Feb 12, 2022 | Highlands Latin | away | L | 17–29 | 13-7 | Louisville Valentines Classic | |
| Tue, Feb 15, 2022 | Beth Haven | home | L | 34–51 | 13-8 | ||
| Fri, Feb 18, 2022 | Iroquois | away | L | 21–46 | 13-9 | ||
| Sun, Feb 20, 2022 | Fern Creek | away | L | 8–50 | 13-10 | 2022 24th District Girls Basketball Tournament |