Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Thu, Dec 2, 2021 | Collins | home | W | 88–25 | 1-0 | ||
| Mon, Dec 6, 2021 | Pulaski County | away | W | 55–42 | 2-0 | ||
| Sat, Dec 11, 2021 | Knox Central | at south laurel | L | 57–68 | 2-1 | Tim Short Showcase | |
| Tue, Dec 14, 2021 | Mercer County | home | W | 64–49 | 3-1 | ||
| Fri, Dec 17, 2021 | Wayne County | home | W | 74–44 | 4-1 | ||
| Mon, Dec 20, 2021 | Jackson County | at corbin | W | 73–49 | 5-1 | ||
| Tue, Dec 21, 2021 | Bell County | at corbin | W | 51–48 | 6-1 | ||
| Wed, Dec 22, 2021 | Corbin | away | L | 58–67 | 6-2 | ||
| Mon, Dec 27, 2021 | Knott County Central | home | W | 62–55 | 7-2 | Lady Ads Tournament | |
| Mon, Dec 27, 2021 | Pleasure Ridge Park | home | W | 73–33 | 8-2 | ||
| Tue, Dec 28, 2021 | Ballard | home | W | 66–28 | 9-2 | ||
| Wed, Dec 29, 2021 | Spencer County | home | W | 63–48 | 10-2 | Lady Ads Tournament | |
| Mon, Jan 3, 2022 | Casey County | away | W | 72–34 | 11-2 | ||
| Mon, Jan 10, 2022 | East Jessamine | home | W | 68–46 | 12-2 | ||
| Fri, Jan 14, 2022 | Danville Christian | at somerset | L | 51–55 | 12-3 | 12th Region All "A" Classic | |
| Tue, Jan 18, 2022 | Lincoln County | away | W | 62–34 | 13-3 | ||
| Fri, Jan 21, 2022 | Boyle County | home | W | 60–36 | 14-3 | ||
| Tue, Jan 25, 2022 | Garrard County | home | W | 78–35 | 15-3 | ||
| Thu, Jan 27, 2022 | North Laurel | home | W | 101–76 | 16-3 | ||
| Tue, Feb 1, 2022 | Garrard County | away | W | 73–42 | 17-3 | ||
| Sat, Feb 5, 2022 | Danville Christian | home | W | 50–35 | 18-3 | ||
| Mon, Feb 7, 2022 | Marion County | home | W | 78–47 | 19-3 | ||
| Tue, Feb 8, 2022 | Boyle County | away | W | 69–33 | 20-3 | ||
| Thu, Feb 10, 2022 | Danville Christian | home | W | 48–24 | 21-3 | ||
| Fri, Feb 11, 2022 | Lincoln County | home | W | 55–42 | 22-3 | ||
| Sat, Feb 12, 2022 | West Carter | at franklin county | W | 66–47 | 23-3 | Bluegrass Orthopedics/Penn Station | |
| Tue, Feb 15, 2022 | Bardstown | away | W | 66–64 | 24-3 | ||
| Fri, Feb 18, 2022 | South Laurel | away | L | 55–62 | 24-4 | ||
| Tue, Feb 22, 2022 | Lincoln County | home | W | 78–47 | 25-4 | 2022 45th District Girls Basketball Tournament | |
| Thu, Feb 24, 2022 | Danville Christian | home | W | 63–37 | 26-4 | 2022 45th District Girls Basketball Tournament | |
| Tue, Mar 1, 2022 | Wayne County | at lincoln county | W | 66–25 | 27-4 | 2022 12th Region Girls Basketball Tournament | |
| Fri, Mar 4, 2022 | Mercer County | at lincoln county | L | 69–76 | 27-5 | 2022 12th Region Girls Basketball Tournament |