Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 30, 2021 | Collins | home | W | 77–39 | 1-0 | ||
| Fri, Dec 3, 2021 | Taylor County | home | W | 70–44 | 2-0 | ||
| Mon, Dec 6, 2021 | McCreary Central | home | W | 74–32 | 3-0 | ||
| Thu, Dec 9, 2021 | East Jessamine | away | L | 55–72 | 3-1 | ||
| Sat, Dec 11, 2021 | Western Hills | home | W | 61–22 | 4-1 | ||
| Tue, Dec 14, 2021 | West Jessamine | home | L | 79–84 | 4-2 | ||
| Fri, Dec 17, 2021 | Fleming County | home | L | 60–71 | 4-3 | ||
| Sat, Dec 18, 2021 | Estill County | away | W | 56–46 | 5-3 | ||
| Mon, Dec 20, 2021 | Robertson County | at bath county | W | 73–36 | 6-3 | ||
| Tue, Dec 21, 2021 | Boone County | at bath county | W | 70–38 | 7-3 | Mike Bromagen Ladycats Legend Tournament | |
| Wed, Dec 22, 2021 | Paris | at bath county | L | 50–55 | 7-4 | ||
| Tue, Dec 28, 2021 | Spencer County | at danville | L | 44–54 | 7-5 | Lady Ads Tournament | |
| Thu, Dec 30, 2021 | Madison Central | away | W | 71–63 | 8-5 | ||
| Tue, Jan 4, 2022 | Boyle County | home | W | 52–22 | 9-5 | ||
| Sat, Jan 8, 2022 | Madison Southern | home | W | 49–42 | 10-5 | Elleman Contracting Winter Classic | |
| Tue, Jan 11, 2022 | Lincoln County | away | W | 50–39 | 11-5 | ||
| Tue, Jan 18, 2022 | Boyle County | away | L | 23–42 | 11-6 | ||
| Tue, Jan 25, 2022 | Danville | away | L | 35–78 | 11-7 | ||
| Fri, Jan 28, 2022 | Lincoln County | home | W | 65–53 | 12-7 | ||
| Tue, Feb 1, 2022 | Danville | home | L | 42–73 | 12-8 | ||
| Mon, Feb 7, 2022 | Danville Christian | home | L | 46–62 | 12-9 | ||
| Thu, Feb 10, 2022 | Casey County | away | W | 57–53 | 13-9 | ||
| Sat, Feb 12, 2022 | Danville Christian | away | L | 51–57 | 13-10 | ||
| Mon, Feb 14, 2022 | Rockcastle County | away | L | 40–55 | 13-11 | ||
| Tue, Feb 15, 2022 | Somerset | home | L | 55–67 | 13-12 | ||
| Thu, Feb 17, 2022 | Bourbon County | away | W | 74–40 | 14-12 | ||
| Tue, Feb 22, 2022 | Danville Christian | at danville | L | 53–56 | 14-13 | 2022 45th District Girls Basketball Tournament |