Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 30, 2021 | Berea | away | L | 51–55 | 0-1 | ||
| Fri, Dec 3, 2021 | Rockcastle County | away | L | 47–62 | 0-2 | ||
| Sat, Dec 4, 2021 | Dixie Heights | away | L | 49–67 | 0-3 | Hoops for Harvest | |
| Tue, Dec 7, 2021 | Knox Central | away | L | 43–59 | 0-4 | ||
| Fri, Dec 10, 2021 | Madison Southern | L | 32–40 | 0-5 | |||
| Wed, Dec 15, 2021 | Conner | home | L | 45–53 | 0-6 | ||
| Thu, Dec 16, 2021 | Whitley County | home | W | 66–59 | 1-6 | ||
| Sat, Dec 18, 2021 | Boyle County | home | W | 51–40 | 2-6 | Adams Buick GMC Holiday Hoopfest | |
| Sun, Dec 19, 2021 | Pulaski County | home | L | 58–62 | 2-7 | Adams Buick GMC Holiday Hoopfest | |
| Mon, Dec 20, 2021 | Harlan | home | W | 64–50 | 3-7 | ||
| Tue, Dec 21, 2021 | Middlesboro | home | W | 64–53 | 4-7 | Adams Buick GMC Holiday Hoopfest | |
| Thu, Dec 30, 2021 | Garrard County | home | L | 63–71 | 4-8 | ||
| Fri, Jan 14, 2022 | Franklin County | away | L | 47–68 | 4-9 | ||
| Sat, Jan 15, 2022 | Frederick Douglass | home | L | 35–54 | 4-10 | ||
| Fri, Jan 21, 2022 | Bryan Station | away | W | 69–56 | 5-10 | ||
| Sat, Jan 22, 2022 | Henry Clay | home | L | 48–56 | 5-11 | ||
| Tue, Jan 25, 2022 | West Jessamine | home | W | 71–63 | 6-11 | ||
| Fri, Jan 28, 2022 | Lafayette | home | W | 49–27 | 7-11 | ||
| Tue, Feb 1, 2022 | Tates Creek | away | W | 71–68 | 8-11 | ||
| Sat, Feb 5, 2022 | Montgomery County | home | L | 50–67 | 8-12 | ||
| Mon, Feb 7, 2022 | Great Crossing | away | W | 58–56 | 9-12 | ||
| Sat, Feb 12, 2022 | Casey County | away | W | 58–43 | 10-12 | ||
| Thu, Feb 17, 2022 | Paul Laurence Dunbar | away | W | 59–55 | 11-12 | ||
| Sat, Feb 19, 2022 | East Jessamine | away | W | 69–67 | 12-12 | ||
| Tue, Feb 22, 2022 | Berea | at alumni coliseum | L | 33–46 | 12-13 | 2022 44th District Girls Basketball Tournament |