Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 30, 2021 | Madison Southern | home | L | 34–55 | 0-1 | ||
| Sat, Dec 4, 2021 | Shelby County | away | W | 74–62 | 1-1 | ||
| Tue, Dec 7, 2021 | Boyle County | away | W | 54–41 | 2-1 | ||
| Thu, Dec 9, 2021 | Garrard County | home | W | 72–55 | 3-1 | ||
| Fri, Dec 10, 2021 | Thomas Nelson | home | W | 64–42 | 4-1 | ||
| Mon, Dec 13, 2021 | Frederick Douglass | away | L | 68–70 | 4-2 | ||
| Sat, Dec 18, 2021 | Woodford County | away | W | 68–56 | 5-2 | ||
| Mon, Dec 20, 2021 | Estill County | at bath county | W | 61–51 | 6-2 | Mike Bromagen Ladycats Legend Tournament | |
| Wed, Dec 22, 2021 | Lewis County | at bath county | L | 50–66 | 6-3 | Mike Bromagen Ladycats Legend Tournament | |
| Sat, Jan 8, 2022 | Lincoln County | away | L | 40–56 | 6-4 | ||
| Sun, Jan 9, 2022 | West Jessamine | away | L | 57–76 | 6-5 | ||
| Mon, Jan 10, 2022 | Danville | away | L | 46–68 | 6-6 | ||
| Tue, Jan 11, 2022 | Mercer County | away | L | 51–80 | 6-7 | ||
| Wed, Jan 19, 2022 | Nelson County | home | L | 58–72 | 6-8 | ||
| Fri, Jan 21, 2022 | Burgin | away | W | 1–0 | 7-8 | COVID Cancelation - RPI per Policy | |
| Sat, Jan 22, 2022 | McCreary Central | away | W | 56–27 | 8-8 | ||
| Tue, Jan 25, 2022 | Mercer County | home | L | 47–55 | 8-9 | ||
| Thu, Jan 27, 2022 | Wayne County | away | W | 69–64 | 9-9 | ||
| Mon, Jan 31, 2022 | Burgin | home | W | 68–43 | 10-9 | ||
| Tue, Feb 1, 2022 | Washington County | home | L | 0–1 | 10-10 | COVID Cancelation - RPI per Policy | |
| Wed, Feb 2, 2022 | Model | home | L | 0–1 | 10-11 | COVID Cancelation - RPI per Policy | |
| Mon, Feb 7, 2022 | Powell County | home | W | 56–52 | 11-11 | ||
| Tue, Feb 8, 2022 | Bryan Station | home | W | 65–53 | 12-11 | ||
| Thu, Feb 10, 2022 | West Jessamine | home | L | 50–55 | 12-12 | ||
| Mon, Feb 14, 2022 | Williamstown | away | W | 50–49 | 13-12 | ||
| Tue, Feb 15, 2022 | Great Crossing | home | L | 50–58 | 13-13 | ||
| Fri, Feb 18, 2022 | Somerset | away | L | 35–74 | 13-14 | ||
| Sat, Feb 19, 2022 | Madison Central | home | L | 67–69 | 13-15 | ||
| Mon, Feb 21, 2022 | West Jessamine | away | L | 51–60 | 13-16 | 2022 46th District Girls Basketball Tournament |