Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 30, 2021 | Madison Central | home | W | 55–51 | 1-0 | ||
| Tue, Dec 7, 2021 | Lafayette | away | W | 48–34 | 2-0 | ||
| Thu, Dec 9, 2021 | Estill County | home | W | 74–37 | 3-0 | ||
| Sat, Dec 11, 2021 | Breathitt County | away | W | 61–46 | 4-0 | Peggy Moore Classic | |
| Tue, Dec 14, 2021 | Paul Laurence Dunbar | away | W | 61–31 | 5-0 | ||
| Sat, Dec 18, 2021 | Raceland | home | W | 70–41 | 6-0 | Berea Holiday Classic | |
| Sun, Dec 19, 2021 | Pleasure Ridge Park | home | W | 54–41 | 7-0 | Berea Holiday Classic | |
| Mon, Dec 20, 2021 | Floyd Central | home | W | 50–45 | 8-0 | ||
| Wed, Dec 22, 2021 | West Jessamine | home | W | 60–53 | 9-0 | ||
| Mon, Dec 27, 2021 | Elliott County | at raceland | W | 50–36 | 10-0 | Ryan Keeton ExP Realty Ohio River Classic | |
| Tue, Dec 28, 2021 | Heritage (Maryville), TN | at raceland | L | 28–46 | 10-1 | ||
| Wed, Dec 29, 2021 | Raceland | away | W | 64–36 | 11-1 | ||
| Sat, Jan 8, 2022 | North Oldham | away | W | 68–49 | 12-1 | Bluegrass Orthopedics/Penn Station | |
| Mon, Jan 10, 2022 | Lexington Christian | at model | W | 65–44 | 13-1 | ||
| Wed, Jan 12, 2022 | Model | away | W | 72–43 | 14-1 | ||
| Sat, Jan 15, 2022 | Sayre | at model | W | 1–0 | 15-1 | COVID Cancelation - RPI per Policy | |
| Tue, Jan 18, 2022 | Franklin County | away | L | 46–59 | 15-2 | ||
| Sat, Jan 22, 2022 | Wayne County | home | W | 57–37 | 16-2 | ||
| Wed, Jan 26, 2022 | Owensboro Catholic | at eku mcbrayer arena | L | 33–39 | 16-3 | All A State Tournament | |
| Fri, Jan 28, 2022 | Madison Southern | W | 44–28 | 17-3 | |||
| Tue, Feb 1, 2022 | Woodford County | home | W | 60–31 | 18-3 | ||
| Sat, Feb 5, 2022 | Lincoln County | home | W | 34–29 | 19-3 | ||
| Mon, Feb 7, 2022 | Bourbon County | home | W | 58–20 | 20-3 | ||
| Tue, Feb 8, 2022 | Spencer County | away | L | 33–52 | 20-4 | ||
| Fri, Feb 11, 2022 | Scott County | away | L | 45–64 | 20-5 | ||
| Sat, Feb 12, 2022 | Mercer County | L | 37–62 | 20-6 | |||
| Mon, Feb 14, 2022 | Lexington Catholic | home | W | 46–43 | 21-6 | ||
| Tue, Feb 15, 2022 | Henry Clay | home | W | 41–39 | 22-6 | ||
| Wed, Feb 16, 2022 | Bryan Station | away | W | 47–38 | 23-6 | ||
| Tue, Feb 22, 2022 | Madison Central | at alumni coliseum | W | 46–33 | 24-6 | 2022 44th District Girls Basketball Tournament | |
| Thu, Feb 24, 2022 | Madison Southern | at alumni coliseum | L | 26–47 | 24-7 | 2022 44th District Girls Basketball Tournament | |
| Mon, Feb 28, 2022 | Lafayette | away | L | 26–46 | 24-8 | 2022 11th Region Girls Basketball Tournament |