Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 29, 2021 | Holmes | home | L | 42–71 | 0-1 | ||
| Tue, Nov 30, 2021 | Pendleton County | away | L | 39–69 | 0-2 | ||
| Fri, Dec 3, 2021 | Grant County | away | L | 31–59 | 0-3 | ||
| Tue, Dec 7, 2021 | Ludlow | home | L | 40–64 | 0-4 | ||
| Fri, Dec 10, 2021 | Williamstown | away | L | 44–51 | 0-5 | ||
| Tue, Dec 14, 2021 | Campbell County | away | L | 39–73 | 0-6 | ||
| Thu, Dec 16, 2021 | Cooper | home | L | 11–69 | 0-7 | ||
| Sat, Dec 18, 2021 | Bracken County | away | L | 34–50 | 0-8 | ||
| Mon, Dec 20, 2021 | Powell County | at bath county | L | 39–67 | 0-9 | ||
| Tue, Dec 21, 2021 | Garrard County | at bath county | L | 38–70 | 0-10 | Mike Bromagen Ladycats Legend Tournament | |
| Wed, Dec 22, 2021 | Bath County | away | L | 29–54 | 0-11 | ||
| Mon, Jan 10, 2022 | Lloyd Memorial | home | L | 43–55 | 0-12 | ||
| Wed, Jan 12, 2022 | Mason County | away | L | 29–65 | 0-13 | ||
| Fri, Jan 14, 2022 | Conner | home | L | 26–72 | 0-14 | ||
| Tue, Jan 18, 2022 | Dixie Heights | away | L | 25–79 | 0-15 | ||
| Fri, Jan 21, 2022 | South Oldham | home | L | 37–65 | 0-16 | ||
| Sat, Jan 22, 2022 | Dayton | home | W | 48–20 | 1-16 | ||
| Mon, Jan 24, 2022 | Simon Kenton | away | L | 22–65 | 1-17 | ||
| Tue, Jan 25, 2022 | Ryle | away | L | 18–72 | 1-18 | ||
| Thu, Jan 27, 2022 | Augusta | home | W | 55–49 | 2-18 | ||
| Sat, Jan 29, 2022 | Cooper | away | L | 10–68 | 2-19 | ||
| Mon, Feb 7, 2022 | Holy Cross (Covington) | away | L | 25–76 | 2-20 | ||
| Wed, Feb 9, 2022 | Ryle | home | L | 22–57 | 2-21 | ||
| Thu, Feb 10, 2022 | Scott | away | L | 40–71 | 2-22 | ||
| Sat, Feb 12, 2022 | St. Henry | away | L | 30–62 | 2-23 | ||
| Mon, Feb 14, 2022 | Walton-Verona | away | L | 36–71 | 2-24 | ||
| Wed, Feb 16, 2022 | Franklin County | away | L | 32–67 | 2-25 | ||
| Tue, Feb 22, 2022 | Ryle | away | L | 17–63 | 2-26 | 2022 33rd District Girls Basketball Tournament |