Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 29, 2021 | Owen County | away | L | 46–60 | 0-1 | ||
| Thu, Dec 2, 2021 | Ryle | away | L | 65–84 | 0-2 | ||
| Sat, Dec 4, 2021 | Newport Central Catholic | home | W | 70–59 | 1-2 | ||
| Mon, Dec 6, 2021 | Lloyd Memorial | away | W | 89–58 | 2-2 | ||
| Wed, Dec 8, 2021 | Scott County | at scott county/great crossing | W | 71–30 | 3-2 | Toyota Classic | |
| Fri, Dec 10, 2021 | Franklin County | at scott county/great crossing | L | 31–54 | 3-3 | ||
| Sat, Dec 11, 2021 | Great Crossing | at scott county/great crossing | L | 70–74 | 3-4 | Toyota Classic | |
| Tue, Dec 14, 2021 | Dixie Heights | away | L | 49–74 | 3-5 | ||
| Fri, Dec 17, 2021 | Walton-Verona | home | W | 69–67 | 4-5 | ||
| Sat, Dec 18, 2021 | Butler | home | W | 75–64 | 5-5 | ||
| Sun, Dec 19, 2021 | South Warren | at lexington catholic | W | 54–42 | 6-5 | ||
| Mon, Dec 20, 2021 | Madisonville-North Hopkins | at lexington catholic | L | 50–55 | 6-6 | ||
| Mon, Jan 3, 2022 | Scott | home | W | 67–33 | 7-6 | ||
| Wed, Jan 5, 2022 | Notre Dame | away | L | 31–68 | 7-7 | ||
| Sat, Jan 8, 2022 | Grant County | away | W | 82–56 | 8-7 | ||
| Mon, Jan 10, 2022 | Holmes | away | W | 74–52 | 9-7 | ||
| Wed, Jan 12, 2022 | Conner | home | L | 51–60 | 9-8 | ||
| Fri, Jan 14, 2022 | Assumption | home | W | 78–76 | 10-8 | ||
| Tue, Jan 18, 2022 | St. Henry | away | W | 64–52 | 11-8 | ||
| Sat, Jan 22, 2022 | Southwestern | away | L | 53–68 | 11-9 | ||
| Mon, Jan 24, 2022 | Boone County | home | W | 65–22 | 12-9 | ||
| Wed, Jan 26, 2022 | Ludlow | away | W | 58–51 | 13-9 | ||
| Mon, Jan 31, 2022 | Williamstown | away | W | 63–44 | 14-9 | ||
| Mon, Feb 7, 2022 | Campbell County | away | W | 58–33 | 15-9 | ||
| Wed, Feb 9, 2022 | Cooper | away | L | 38–57 | 15-10 | ||
| Mon, Feb 14, 2022 | Highlands | home | W | 59–39 | 16-10 | ||
| Wed, Feb 16, 2022 | Holy Cross (Covington) | away | L | 47–62 | 16-11 | ||
| Mon, Feb 21, 2022 | Williamstown | at walton-verona | W | 68–24 | 17-11 | 2022 32nd District Girls Basketball Tournament | |
| Thu, Feb 24, 2022 | Walton-Verona | away | L | 54–56 | 17-12 | 2022 32nd District Girls Basketball Tournament | |
| Tue, Mar 1, 2022 | Anderson County | at grant county | L | 67–77 | 17-13 | 2022 8th Region Girls Basketball Tournament |