Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 30, 2021 | Newport Central Catholic | home | L | 56–62 | 0-1 | ||
| Sat, Dec 4, 2021 | Henderson County | at owensboro catholic | L | 28–64 | 0-2 | ||
| Tue, Dec 7, 2021 | Bullitt East | away | L | 36–55 | 0-3 | ||
| Fri, Dec 10, 2021 | Male | away | L | 57–63 | 0-4 | ||
| Tue, Dec 14, 2021 | Christian Academy-Louisville | home | L | 45–59 | 0-5 | ||
| Fri, Dec 17, 2021 | Central | home | L | 52–55 | 0-6 | ||
| Sat, Dec 18, 2021 | Simon Kenton | away | L | 64–75 | 0-7 | ||
| Mon, Dec 20, 2021 | Breckinridge County | at elizabethtown | L | 31–50 | 0-8 | Cochran Mechanical/Smith Realtors Holiday H… | |
| Tue, Dec 21, 2021 | North Oldham | at elizabethtown | W | 56–49 | 1-8 | ||
| Wed, Dec 22, 2021 | Mercer County | at elizabethtown | W | 60–49 | 2-8 | ||
| Wed, Dec 29, 2021 | Columbus North (Columbus), IN | L | 0–1 | 2-9 | COVID Cancelation - RPI per Policy | ||
| Tue, Jan 11, 2022 | Doss | away | W | 1–0 | 3-9 | (forfeit) | |
| Tue, Jan 11, 2022 | Jeffersonville, IN | home | W | 1–0 | 4-9 | (forfeit) | |
| Wed, Jan 12, 2022 | DuPont Manual | away | L | 38–61 | 4-10 | ||
| Fri, Jan 14, 2022 | Mercy Academy | home | L | 46–55 | 4-11 | ||
| Fri, Jan 21, 2022 | Iroquois | home | W | 53–15 | 5-11 | ||
| Mon, Jan 24, 2022 | Portland Christian | at various sites | W | 64–27 | 6-11 | Republic Bank Louisville Invitational Tourn… | |
| Tue, Jan 25, 2022 | Sacred Heart | at various sites | L | 25–72 | 6-12 | ||
| Sat, Jan 29, 2022 | Anderson County | at various sites | L | 42–68 | 6-13 | Republic Bank Louisville Invitational Tourn… | |
| Tue, Feb 1, 2022 | Collins | home | W | 72–35 | 7-13 | ||
| Wed, Feb 2, 2022 | Western | home | W | 1–0 | 8-13 | (forfeit) | |
| Tue, Feb 8, 2022 | Assumption | away | L | 69–73 | 8-14 | ||
| Thu, Feb 10, 2022 | Pleasure Ridge Park | W | 51–40 | 9-14 | |||
| Sat, Feb 12, 2022 | Russell | home | L | 49–74 | 9-15 | ||
| Tue, Feb 15, 2022 | Spencer County | away | L | 32–54 | 9-16 | ||
| Fri, Feb 18, 2022 | Whitefield Academy | home | L | 47–52 | 9-17 | ||
| Mon, Feb 21, 2022 | Western | at iroquois | W | 66–7 | 10-17 | 2022 22nd District Girls Basketball Tournament | |
| Wed, Feb 23, 2022 | Iroquois | at desales | W | 56–14 | 11-17 | 2022 22nd District Girls Basketball Tournament | |
| Mon, Feb 28, 2022 | Mercy Academy | home | L | 35–60 | 11-18 | 2022 6th Region Girls Basketball Tournament |