Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 29, 2021 | Bracken County | home | L | 42–52 | 0-1 | ||
| Wed, Dec 1, 2021 | St. Patrick | home | L | 32–69 | 0-2 | ||
| Mon, Dec 6, 2021 | Augusta | away | L | 57–65 | 0-3 | ||
| Wed, Dec 8, 2021 | Mason County | home | L | 36–64 | 0-4 | ||
| Sat, Dec 11, 2021 | Williamstown | away | 0–0 | COVID Cancelation - RPI per Policy | |||
| Mon, Dec 13, 2021 | Frankfort | home | L | 56–72 | 0-5 | ||
| Wed, Dec 15, 2021 | Fleming County | away | L | 51–68 | 0-6 | ||
| Fri, Dec 17, 2021 | Nicholas County | home | L | 62–71 | 0-7 | ||
| Mon, Dec 20, 2021 | Garrard County | at bath county | L | 36–73 | 0-8 | ||
| Tue, Dec 21, 2021 | Bath County | away | L | 48–80 | 0-9 | Mike Bromagen Ladycats Legend Tournament | |
| Wed, Dec 22, 2021 | Estill County | at bath county | L | 35–78 | 0-10 | ||
| Thu, Dec 30, 2021 | Highlands | away | L | 39–76 | 0-11 | ||
| Mon, Jan 3, 2022 | Fleming County | home | L | 27–81 | 0-12 | ||
| Sat, Jan 8, 2022 | Calvary Christian | away | W | 51–10 | 1-12 | 10th Region All "A" Classic | |
| Mon, Jan 10, 2022 | Paris | at bracken county | L | 39–54 | 1-13 | ||
| Fri, Jan 14, 2022 | Pendleton County | home | L | 23–54 | 1-14 | ||
| Wed, Jan 19, 2022 | Bracken County | away | L | 36–63 | 1-15 | ||
| Fri, Jan 21, 2022 | Harrison County | away | L | 29–65 | 1-16 | ||
| Sat, Jan 22, 2022 | Ludlow | home | L | 25–66 | 1-17 | ||
| Sat, Jan 29, 2022 | Dayton | home | L | 53–57 | 1-18 | (overtime) | |
| Tue, Feb 1, 2022 | Pendleton County | away | L | 35–67 | 1-19 | ||
| Wed, Feb 2, 2022 | Harrison County | home | L | 28–66 | 1-20 | ||
| Wed, Feb 9, 2022 | Lewis County | home | L | 41–65 | 1-21 | ||
| Thu, Feb 10, 2022 | Fairview | home | W | 64–32 | 2-21 | ||
| Sat, Feb 12, 2022 | Rose Hill Christian | home | W | 55–35 | 3-21 | ||
| Mon, Feb 14, 2022 | Nicholas County | away | L | 34–69 | 3-22 | ||
| Wed, Feb 16, 2022 | St. Patrick | away | L | 43–65 | 3-23 | ||
| Fri, Feb 18, 2022 | Paris | away | L | 15–73 | 3-24 | ||
| Sat, Feb 19, 2022 | Augusta | home | L | 39–60 | 3-25 | ||
| Mon, Feb 21, 2022 | Nicholas County | away | L | 26–62 | 3-26 | 2022 38th District Girls Basketball Tournament |