Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2010 | Bellevue | away | W | 33–19 | 1-0 | ||
| Fri, Aug 27, 2010 | Belfry | at pikeville/shelby valley | L | 14–20 | 1-1 | ||
| Sat, Sep 11, 2010 | Beechwood | at bellevue | L | 21–28 | 1-2 | ||
| Fri, Sep 17, 2010 | Conner | away | W | 41–21 | 2-2 | ||
| Sat, Sep 25, 2010 | Columbus Bishop Ready, OH | home | L | 41–46 | 2-3 | ||
| Fri, Oct 1, 2010 | Holy Cross (Louisville) | away | L | 28–56 | 2-4 | ||
| Fri, Oct 8, 2010 | Newport Central Catholic | home | L | 14–28 | 2-5 | ||
| Fri, Oct 15, 2010 | Lloyd Memorial | away | W | 50–6 | 3-5 | ||
| Sat, Oct 23, 2010 | Newport | home | W | 55–21 | 4-5 | ||
| Fri, Oct 29, 2010 | Bishop Brossart | away | W | 56–14 | 5-5 | ||
| Fri, Nov 5, 2010 | Carroll County | home | W | 55–17 | 6-5 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | DeSales | away | W | 26–14 | 7-5 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Newport Central Catholic | away | L | 21–56 | 7-6 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl |