Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Sat, Aug 21, 2010 | Oldham County | W | 22–20 | 1-0 | |||
| Fri, Aug 27, 2010 | Scott | home | W | 46–6 | 2-0 | ||
| Fri, Sep 3, 2010 | Lloyd Memorial | away | W | 36–0 | 3-0 | ||
| Fri, Sep 10, 2010 | Dixie Heights | away | L | 26–41 | 3-1 | ||
| Fri, Sep 17, 2010 | Holy Cross (Covington) | home | L | 21–41 | 3-2 | ||
| Fri, Sep 24, 2010 | Simon Kenton | home | L | 6–48 | 3-3 | ||
| Fri, Oct 1, 2010 | Boone County | away | W | 27–21 | 4-3 | ||
| Fri, Oct 8, 2010 | Campbell County | away | L | 13–14 | 4-4 | ||
| Fri, Oct 15, 2010 | Ryle | home | L | 6–49 | 4-5 | ||
| Fri, Oct 22, 2010 | Cooper | home | W | 46–40 | 5-5 | ||
| Fri, Nov 5, 2010 | Henry Clay | away | L | 20–32 | 5-6 | 2010 Class 6A KHSAA Commonwealth Gridiron Bowl |