Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Sat, Aug 21, 2010 | Warren Central | at wku | W | 15–8 | 1-0 | ||
| Sat, Aug 28, 2010 | Clarksville, TN | at stadium of champions, hopkinsville | W | 26–13 | 2-0 | ||
| Fri, Sep 3, 2010 | Henderson County | home | W | 42–14 | 3-0 | ||
| Fri, Sep 10, 2010 | Pleasure Ridge Park | away | W | 39–32 | 4-0 | ||
| Fri, Sep 17, 2010 | Hopkinsville | away | W | 42–15 | 5-0 | ||
| Fri, Sep 24, 2010 | Madisonville-North Hopkins | home | W | 27–24 | 6-0 | ||
| Fri, Oct 1, 2010 | Owensboro | away | W | 21–0 | 7-0 | ||
| Fri, Oct 8, 2010 | Ohio County | home | W | 71–7 | 8-0 | ||
| Fri, Oct 22, 2010 | Oakland, TN | home | L | 8–35 | 8-1 | ||
| Fri, Oct 29, 2010 | Boyle County | away | L | 33–49 | 8-2 | ||
| Fri, Nov 5, 2010 | Barren County | home | W | 54–0 | 9-2 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Bowling Green | home | W | 14–10 | 10-2 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Warren Central | away | W | 27–26 | 11-2 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 26, 2010 | John Hardin | away | W | 45–20 | 12-2 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Sat, Dec 4, 2010 | Highlands | at houchens-l.t. smith stadium, wku | L | 0–50 | 12-3 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl |