Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Sat, Aug 28, 2010 | Marion County | away | W | 35–14 | 1-0 | ||
| Fri, Sep 3, 2010 | Meade County | away | W | 28–21 | 2-0 | ||
| Fri, Sep 10, 2010 | North Hardin | home | W | 27–6 | 3-0 | ||
| Fri, Sep 17, 2010 | Nelson County | home | W | 21–0 | 4-0 | ||
| Fri, Sep 24, 2010 | Doss | away | W | 39–3 | 5-0 | ||
| Fri, Oct 1, 2010 | Paul Laurence Dunbar | home | W | 63–14 | 6-0 | ||
| Fri, Oct 8, 2010 | Iroquois | home | W | 57–0 | 7-0 | ||
| Fri, Oct 15, 2010 | Waggener | away | W | 49–0 | 8-0 | ||
| Fri, Oct 22, 2010 | Bullitt Central | home | W | 52–7 | 9-0 | ||
| Fri, Oct 29, 2010 | Central Hardin | away | W | 49–13 | 10-0 | ||
| Fri, Nov 5, 2010 | Jeffersontown | home | W | 65–22 | 11-0 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Oldham County | home | W | 41–17 | 12-0 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Anderson County | away | W | 28–24 | 13-0 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 26, 2010 | Christian County | home | L | 20–45 | 13-1 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl |