Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2010 | Evansville F.J. Reitz, IN | home | L | 20–34 | 0-1 | ||
| Sat, Aug 28, 2010 | Evansville North, IN | away | W | 40–21 | 1-1 | ||
| Fri, Sep 3, 2010 | Christian County | away | L | 14–42 | 1-2 | ||
| Fri, Sep 10, 2010 | Madisonville-North Hopkins | home | W | 33–21 | 2-2 | ||
| Fri, Sep 24, 2010 | Daviess County | away | W | 52–7 | 3-2 | ||
| Fri, Oct 1, 2010 | Muhlenberg County | home | W | 48–7 | 4-2 | ||
| Fri, Oct 8, 2010 | Graves County | home | W | 28–17 | 5-2 | ||
| Fri, Oct 15, 2010 | Marshall County | away | W | 49–6 | 6-2 | ||
| Fri, Oct 22, 2010 | Apollo | away | W | 56–7 | 7-2 | ||
| Fri, Oct 29, 2010 | Owensboro | home | W | 17–14 | 8-2 | ||
| Fri, Nov 12, 2010 | Fern Creek | home | W | 56–35 | 9-2 | 2010 Class 6A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Male | away | L | 7–14 | 9-3 | 2010 Class 6A KHSAA Commonwealth Gridiron Bowl |