Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Sat, Aug 21, 2010 | Southwestern | at wku | W | 52–0 | 1-0 | ||
| Fri, Aug 27, 2010 | Daviess County | at kwc steel stadium/rash stadium | W | 66–0 | 2-0 | ||
| Fri, Sep 3, 2010 | Franklin-Simpson | home | W | 35–0 | 3-0 | ||
| Fri, Sep 10, 2010 | Warren East | away | W | 53–14 | 4-0 | ||
| Fri, Sep 17, 2010 | Owensboro | away | W | 44–20 | 5-0 | ||
| Fri, Sep 24, 2010 | Trinity (Louisville) | home | L | 12–14 | 5-1 | ||
| Fri, Oct 1, 2010 | Grayson County | away | W | 41–27 | 6-1 | ||
| Fri, Oct 15, 2010 | Doss | home | W | 36–0 | 7-1 | ||
| Fri, Oct 22, 2010 | Warren Central | away | L | 14–17 | 7-2 | ||
| Fri, Oct 29, 2010 | Barren County | home | W | 52–6 | 8-2 | ||
| Fri, Nov 5, 2010 | Madisonville-North Hopkins | home | W | 25–0 | 9-2 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Christian County | away | L | 10–14 | 9-3 | 2010 Class 5A KHSAA Commonwealth Gridiron Bowl |