Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2010 | Evansville Central, IN | home | L | 7–27 | 0-1 | ||
| Fri, Aug 27, 2010 | Indianapolis Broad Ripple, IN | away | W | 36–13 | 1-1 | ||
| Fri, Sep 3, 2010 | North Oldham | home | W | 37–6 | 2-1 | ||
| Fri, Sep 10, 2010 | Lexington Christian | away | L | 14–20 | 2-2 | overtime | |
| Fri, Sep 17, 2010 | Holy Cross (Louisville) | home | L | 17–25 | 2-3 | ||
| Fri, Sep 24, 2010 | Shawnee | home | W | 61–6 | 3-3 | ||
| Fri, Oct 8, 2010 | Carroll County | home | W | 69–12 | 4-3 | ||
| Fri, Oct 15, 2010 | DeSales | at dupont manual | L | 26–31 | 4-4 | ||
| Fri, Oct 22, 2010 | Owen County | away | W | 60–6 | 5-4 | ||
| Fri, Oct 29, 2010 | Kentucky Country Day | home | W | 40–22 | 6-4 | ||
| Fri, Nov 5, 2010 | Newport | home | W | 30–21 | 7-4 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Newport Central Catholic | away | L | 21–51 | 7-5 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl |