Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2021 | Campbell County | away | L | 0–21 | 0-1 | ||
| Fri, Aug 27, 2021 | Holmes | away | W | 12–8 | 1-1 | ||
| Fri, Sep 3, 2021 | Roger Bacon (Cincinnati), OH | home | L | 13–48 | 1-2 | ||
| Fri, Sep 10, 2021 | Walton-Verona | away | W | 23–14 | 2-2 | ||
| Fri, Sep 17, 2021 | Holy Cross (Covington) | home | W | 48–14 | 3-2 | ||
| Sat, Sep 25, 2021 | Newport | away | W | 43–14 | 4-2 | ||
| Fri, Oct 1, 2021 | Open | 0–0 | |||||
| Thu, Oct 7, 2021 | Ludlow | home | W | 69–28 | 5-2 | ||
| Fri, Oct 15, 2021 | Dayton | home | W | 23–6 | 6-2 | ||
| Fri, Oct 22, 2021 | Bellevue | away | W | 55–14 | 7-2 | ||
| Fri, Oct 29, 2021 | Beechwood | away | L | 7–70 | 7-3 | ||
| Thu, Nov 4, 2021 | Bellevue | home | W | 36–20 | 8-3 | 2021 Class 1A 2021 UK Orthopaedics State Football Finals | |
| Fri, Nov 12, 2021 | Dayton | home | W | 54–6 | 9-3 | 2021 Class 1A 2021 UK Orthopaedics State Football Finals | |
| Fri, Nov 19, 2021 | Russellville | away | L | 0–21 | 9-4 | 2021 Class 1A 2021 UK Orthopaedics State Football Finals |