Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2021 | Bishop Brossart | away | L | 0–28 | 0-1 | ||
| Mon, Aug 30, 2021 | Pendleton County | home | W | 20–16 | 1-1 | ||
| Fri, Sep 3, 2021 | Western Hills | home | W | 14–6 | 2-1 | ||
| Fri, Sep 10, 2021 | Estill County | home | L | 8–50 | 2-2 | ||
| Fri, Sep 17, 2021 | Sayre | away | L | 8–42 | 2-3 | ||
| Fri, Sep 24, 2021 | Fairview | away | W | 42–8 | 3-3 | ||
| Fri, Oct 1, 2021 | Open | 0–0 | |||||
| Fri, Oct 8, 2021 | Bellevue | home | W | 44–7 | 4-3 | ||
| Fri, Oct 15, 2021 | Newport Central Catholic | away | L | 6–23 | 4-4 | ||
| Fri, Oct 22, 2021 | Ludlow | home | L | 6–49 | 4-5 | ||
| Fri, Oct 29, 2021 | Eminence | away | L | 18–27 | 4-6 | ||
| Fri, Nov 5, 2021 | Ludlow | away | W | 20–7 | 5-6 | 2021 Class 1A 2021 UK Orthopaedics State Football Finals | |
| Fri, Nov 12, 2021 | Newport Central Catholic | away | L | 6–54 | 5-7 | 2021 Class 1A 2021 UK Orthopaedics State Football Finals |