Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 30, 2021 | Hancock County | away | W | 75–66 | 1-0 | ||
| Fri, Dec 3, 2021 | Meade County | at owensboro catholic | L | 42–55 | 1-1 | ||
| Sat, Dec 4, 2021 | Pulaski County | at muhlenberg county | L | 29–53 | 1-2 | ||
| Tue, Dec 7, 2021 | University Heights | away | W | 66–23 | 2-2 | ||
| Fri, Dec 10, 2021 | Owensboro | home | W | 47–31 | 3-2 | ||
| Sat, Dec 11, 2021 | Logan County | home | L | 43–48 | 3-3 | ||
| Tue, Dec 14, 2021 | Ohio County | away | W | 46–18 | 4-3 | ||
| Fri, Dec 17, 2021 | Owensboro Catholic | away | L | 45–57 | 4-4 | ||
| Mon, Dec 20, 2021 | Union County | at owensboro sportscenter | W | 52–48 | 5-4 | Independence Bank Kentucky-Indiana Classic | |
| Tue, Dec 21, 2021 | Butler County | at owensboro sportscenter | W | 47–39 | 6-4 | ||
| Mon, Dec 27, 2021 | Lyon County | at caldwell county | W | 62–40 | 7-4 | ||
| Tue, Dec 28, 2021 | Hickman County | at caldwell county | W | 73–26 | 8-4 | ||
| Mon, Jan 3, 2022 | Evansville Reitz (Evansville), IN | home | W | 1–0 | 9-4 | COVID Cancelation - RPI per Policy | |
| Tue, Jan 11, 2022 | Grayson County | home | W | 52–21 | 10-4 | ||
| Fri, Jan 14, 2022 | Apollo | home | L | 44–50 | 10-5 | ||
| Sat, Jan 15, 2022 | Trigg County | away | W | 52–38 | 11-5 | ||
| Tue, Jan 18, 2022 | Christian County | away | W | 57–53 | 12-5 | ||
| Thu, Jan 20, 2022 | Breckinridge County | home | L | 30–48 | 12-6 | ||
| Fri, Jan 21, 2022 | Henderson County | home | L | 40–61 | 12-7 | ||
| Tue, Jan 25, 2022 | Hopkinsville | home | L | 0–1 | 12-8 | COVID Cancelation - RPI per Policy | |
| Tue, Feb 1, 2022 | McLean County | away | W | 54–43 | 13-8 | ||
| Sat, Feb 5, 2022 | Webster County | at owensboro sportscenter | L | 39–49 | 13-9 | Ruoff Mortgage Classic | |
| Mon, Feb 7, 2022 | Owensboro Catholic | home | L | 28–51 | 13-10 | ||
| Wed, Feb 9, 2022 | Owensboro | away | W | 47–44 | 14-10 | ||
| Fri, Feb 11, 2022 | Apollo | away | W | 44–40 | 15-10 | ||
| Sat, Feb 12, 2022 | Lyon County | away | W | 65–38 | 16-10 | Akridge Ace Hardware Shootout | |
| Tue, Feb 15, 2022 | Madisonville-North Hopkins | away | L | 57–64 | 16-11 | ||
| Wed, Feb 16, 2022 | Trinity (Whitesville) | home | W | 59–50 | 17-11 | ||
| Thu, Feb 17, 2022 | Edmonson County | away | W | 60–47 | 18-11 | ||
| Mon, Feb 21, 2022 | Apollo | home | L | 44–51 | 18-12 | 2022 9th District Girls Basketball Tournament |