Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Dec 3, 2021 | Logan County | away | W | 44–40 | 1-0 | ||
| Mon, Dec 6, 2021 | Warren East | away | W | 64–39 | 2-0 | ||
| Sat, Dec 11, 2021 | LaRue County | home | W | 52–44 | 3-0 | ||
| Mon, Dec 13, 2021 | Todd County Central | home | W | 47–43 | 4-0 | ||
| Fri, Dec 17, 2021 | Russellville | home | W | 45–34 | 5-0 | ||
| Mon, Dec 20, 2021 | Muhlenberg County | at owensboro sportscenter | W | 51–40 | 6-0 | Independence Bank Kentucky-Indiana Classic | |
| Tue, Dec 21, 2021 | Daviess County | at owensboro sportscenter | L | 39–47 | 6-1 | ||
| Tue, Dec 28, 2021 | Hendersonville, TN | at gatlinburg, tenn. | W | 59–53 | 7-1 | ||
| Wed, Dec 29, 2021 | St. Agnes Academy (Memphis), TN | at gatlinburg, tenn. | W | 57–43 | 8-1 | Smokey Mountain Classic | |
| Mon, Jan 3, 2022 | Muhlenberg County | home | W | 60–34 | 9-1 | ||
| Tue, Jan 4, 2022 | Russellville | away | W | 44–33 | 10-1 | ||
| Fri, Jan 14, 2022 | Grayson County | away | W | 45–20 | 11-1 | ||
| Sat, Jan 15, 2022 | University Heights | away | W | 74–32 | 12-1 | ||
| Tue, Jan 18, 2022 | Hancock County | away | W | 61–31 | 13-1 | ||
| Sat, Jan 22, 2022 | Edmonson County | home | W | 48–37 | 14-1 | ||
| Mon, Jan 24, 2022 | Metcalfe County | home | W | 70–64 | 15-1 | (overtime) | |
| Fri, Jan 28, 2022 | Trinity (Whitesville) | home | W | 44–35 | 16-1 | ||
| Sat, Jan 29, 2022 | Dawson Springs | away | W | 72–39 | 17-1 | ||
| Mon, Jan 31, 2022 | Trinity (Whitesville) | away | W | 49–45 | 18-1 | ||
| Tue, Feb 1, 2022 | Franklin-Simpson | away | L | 49–65 | 18-2 | ||
| Sat, Feb 5, 2022 | Grayson County | home | W | 54–38 | 19-2 | ||
| Tue, Feb 8, 2022 | South Warren | home | W | 56–55 | 20-2 | (overtime) | |
| Fri, Feb 11, 2022 | Edmonson County | away | W | 44–42 | 21-2 | ||
| Sat, Feb 12, 2022 | University Heights | home | W | 56–34 | 22-2 | ||
| Mon, Feb 14, 2022 | Ohio County | home | L | 51–52 | 22-3 | (overtime) | |
| Tue, Feb 15, 2022 | Owensboro | home | W | 54–47 | 23-3 | ||
| Mon, Feb 21, 2022 | Grayson County | home | W | 48–36 | 24-3 | 2022 12th District Girls Basketball Tournament | |
| Thu, Feb 24, 2022 | Edmonson County | home | W | 49–26 | 25-3 | 2022 12th District Girls Basketball Tournament | |
| Mon, Feb 28, 2022 | Breckinridge County | at owensboro sportscenter | L | 46–55 | 25-4 | 2022 3rd Region Girls Basketball Tournament |