Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Thu, Nov 30, 2000 | Notre Dame | at boone county | L | 44–67 | 0-1 | Lady Rebel Classic | |
| Fri, Dec 1, 2000 | Boone County | away | L | 46–74 | 0-2 | Lady Rebel Classic | |
| Sat, Dec 2, 2000 | Madison Central | away | L | 53–79 | 0-3 | ||
| Mon, Dec 4, 2000 | Rowan County | away | W | 67–66 | 1-3 | (overtime) EKC Tournament | |
| Tue, Dec 5, 2000 | West Carter | at bath county | L | 50–82 | 1-4 | EKC Tournament | |
| Mon, Dec 11, 2000 | Boyd County | home | L | 51–54 | 1-5 | ||
| Thu, Dec 14, 2000 | Ashland Blazer | home | W | 51–41 | 2-5 | ||
| Mon, Dec 18, 2000 | Greenup County | home | W | 74–50 | 3-5 | ||
| Wed, Dec 27, 2000 | George Rogers Clark | at east carter | W | 63–47 | 4-5 | Queen of the Bluegrass | |
| Thu, Dec 28, 2000 | Prestonsburg | at east carter | W | 72–52 | 5-5 | Queen of the Bluegrass | |
| Fri, Dec 29, 2000 | Paul Laurence Dunbar | at east carter | L | 57–70 | 5-6 | Queen of the Bluegrass | |
| Thu, Jan 4, 2001 | Ashland Blazer | away | W | 49–46 | 6-6 | ||
| Sat, Jan 6, 2001 | Fairview | home | W | 73–44 | 7-6 | ||
| Mon, Jan 8, 2001 | East Carter | home | L | 45–77 | 7-7 | ||
| Thu, Jan 11, 2001 | Lewis County | away | W | 87–64 | 8-7 | ||
| Mon, Jan 15, 2001 | Mason County | home | L | 47–60 | 8-8 | ||
| Thu, Jan 25, 2001 | Boyd County | away | L | 64–66 | 8-9 | (overtime) | |
| Fri, Jan 26, 2001 | Rowan County | home | W | 55–51 | 9-9 | ||
| Mon, Jan 29, 2001 | Raceland | away | W | 77–47 | 10-9 | ||
| Thu, Feb 1, 2001 | Lawrence County | away | W | 59–44 | 11-9 | ||
| Sat, Feb 3, 2001 | South Point, OH | home | |||||
| Mon, Feb 5, 2001 | Bath County | home | W | 66–34 | 12-9 | ||
| Thu, Feb 8, 2001 | West Carter | away | L | 41–63 | 12-10 | ||
| Mon, Feb 12, 2001 | Morgan County | home | W | 60–37 | 13-10 | ||
| Thu, Feb 15, 2001 | Greenup County | away | W | 55–48 | 14-10 | ||
| Sat, Feb 17, 2001 | Johnson Central | home | L | 44–60 | 14-11 | ||
| Wed, Feb 28, 2001 | Raceland | away | W | 73–40 | 15-11 | 2001 63rd District Girls Basketball Tournament | |
| Fri, Mar 2, 2001 | Greenup County | at raceland | W | 75–36 | 16-11 | 2001 63rd District Girls Basketball Tournament | |
| Mon, Mar 5, 2001 | West Carter | home | L | 50–69 | 16-12 | 2001 16th Region Girls Basketball Tournament |