Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Mon, Nov 27, 2000 | Hickman County | away | W | 95–40 | 1-0 | ||
| Tue, Dec 5, 2000 | Ballard Memorial | home | W | 95–18 | 2-0 | ||
| Mon, Dec 11, 2000 | Calloway County | home | W | 74–34 | 3-0 | ||
| Tue, Dec 12, 2000 | Mayfield | away | W | 49–38 | 4-0 | ||
| Sat, Dec 16, 2000 | MS Douglas, FL | at coral springs, fl | W | 62–41 | 5-0 | Kruel Classic | |
| Mon, Dec 18, 2000 | Timpview, UT | at coral springs, fl | W | 54–50 | 6-0 | Kruel Classic | |
| Tue, Dec 19, 2000 | Paul Laurence Dunbar | at coral springs, fl | L | 37–47 | 6-1 | Kruel Classic | |
| Wed, Dec 20, 2000 | Cookeville, TN | at coral springs, fl | L | 28–46 | 6-2 | Kruel Classic | |
| Thu, Jan 4, 2001 | Marshall County | away | W | 43–42 | 7-2 | (overtime) | |
| Fri, Jan 5, 2001 | St. Mary | home | W | 64–31 | 8-2 | ||
| Tue, Jan 9, 2001 | Fulton City | home | W | 80–35 | 9-2 | ||
| Sat, Jan 13, 2001 | Webster County | home | W | 57–34 | 10-2 | ||
| Thu, Jan 18, 2001 | Paducah Tilghman | home | W | 81–40 | 11-2 | ||
| Sat, Jan 20, 2001 | Obion County, TN | home | W | 42–39 | 12-2 | ||
| Tue, Jan 23, 2001 | St. Mary | away | W | 58–32 | 13-2 | ||
| Thu, Jan 25, 2001 | Mayfield | home | W | 54–28 | 14-2 | ||
| Tue, Jan 30, 2001 | Paducah Tilghman | away | W | 71–40 | 15-2 | ||
| Fri, Feb 2, 2001 | Ballard Memorial | away | W | 72–15 | 16-2 | ||
| Sat, Feb 3, 2001 | Hopkins County Central | home | W | 71–35 | 17-2 | ||
| Mon, Feb 5, 2001 | Marshall County | home | W | 57–53 | 18-2 | ||
| Thu, Feb 8, 2001 | Carlisle County | away | W | 45–33 | 19-2 | (corrected score) | |
| Mon, Feb 12, 2001 | Calloway County | away | W | 63–38 | 20-2 | ||
| Thu, Feb 15, 2001 | Fulton City | away | W | 60–42 | 21-2 | ||
| Mon, Feb 19, 2001 | Fulton County | home | W | 86–33 | 22-2 | ||
| Tue, Feb 20, 2001 | Reidland | home | W | 66–26 | 23-2 | ||
| Thu, Feb 22, 2001 | Lone Oak | away | L | 39–54 | 23-3 | ||
| Tue, Feb 27, 2001 | Ballard Memorial | at st. mary | W | 66–23 | 24-3 | 2001 3rd District Girls Basketball Tournament | |
| Fri, Mar 2, 2001 | St. Mary | away | W | 59–27 | 25-3 | 2001 3rd District Girls Basketball Tournament | |
| Thu, Mar 8, 2001 | Calloway County | at murray state university | W | 52–25 | 26-3 | 2001 1st Region Girls Basketball Tournament | |
| Mon, Mar 12, 2001 | Lone Oak | at murray state university | W | 44–38 | 27-3 | 2001 1st Region Girls Basketball Tournament | |
| Tue, Mar 13, 2001 | Marshall County | at murray state university | L | 44–51 | 27-4 | 2001 1st Region Girls Basketball Tournament |