Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2021 | Lexington Catholic | home | L | 21–24 | 0-1 | ||
| Fri, Aug 27, 2021 | Conner | home | W | 40–7 | 1-1 | ||
| Fri, Sep 3, 2021 | Cooper | away | W | 14–7 | 2-1 | ||
| Fri, Sep 10, 2021 | DeSales | home | W | 49–7 | 3-1 | ||
| Fri, Sep 17, 2021 | Highlands | away | W | 27–13 | 4-1 | ||
| Fri, Sep 24, 2021 | Open | 0–0 | |||||
| Fri, Oct 1, 2021 | St. Xavier | home | L | 3–13 | 4-2 | ||
| Fri, Oct 8, 2021 | Campbell County | away | W | 44–11 | 5-2 | ||
| Fri, Oct 15, 2021 | Dixie Heights | away | W | 13–12 | 6-2 | ||
| Sat, Oct 23, 2021 | Simon Kenton | home | W | 47–22 | 7-2 | ||
| Fri, Oct 29, 2021 | Covington Catholic | away | L | 3–10 | 7-3 | ||
| Thu, Nov 4, 2021 | Campbell County | home | W | 35–7 | 8-3 | 2021 Class 6A 2021 UK Orthopaedics State Football Finals | |
| Fri, Nov 12, 2021 | Dixie Heights | home | W | 36–7 | 9-3 | 2021 Class 6A 2021 UK Orthopaedics State Football Finals | |
| Fri, Nov 19, 2021 | Trinity (Louisville) | home | L | 18–38 | 9-4 | 2021 Class 6A 2021 UK Orthopaedics State Football Finals |