Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Sat, Aug 21, 2021 | Bowling Green | at western kentucky university | W | 21–18 | 1-0 | Rafferty's Bowl | |
| Fri, Aug 27, 2021 | Simon Kenton | away | W | 53–38 | 2-0 | ||
| Fri, Sep 3, 2021 | Campbell County | home | W | 42–7 | 3-0 | ||
| Fri, Sep 10, 2021 | Archbishop McNicholas (Cincinnati), OH | away | L | 21–27 | 3-1 | ||
| Fri, Sep 17, 2021 | Ryle | home | L | 13–27 | 3-2 | ||
| Fri, Sep 24, 2021 | Dixie Heights | away | L | 21–28 | 3-3 | ||
| Fri, Oct 1, 2021 | Conner | home | L | 13–21 | 3-4 | ||
| Fri, Oct 8, 2021 | Boone County | away | W | 41–0 | 4-4 | ||
| Fri, Oct 15, 2021 | Covington Catholic | home | L | 7–8 | 4-5 | ||
| Fri, Oct 22, 2021 | Cooper | away | W | 35–7 | 5-5 | ||
| Fri, Oct 29, 2021 | Open | 0–0 | |||||
| Fri, Nov 5, 2021 | Covington Catholic | away | L | 8–38 | 5-6 | 2021 Class 5A 2021 UK Orthopaedics State Football Finals |