Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2010 | Madisonville-North Hopkins | away | W | 7–0 | 1-0 | ||
| Fri, Aug 27, 2010 | Calloway County | W | 28–21 | 2-0 | |||
| Fri, Sep 3, 2010 | Fulton City | home | W | 57–0 | 3-0 | ||
| Fri, Sep 10, 2010 | Fulton County | home | W | 55–6 | 4-0 | ||
| Fri, Sep 17, 2010 | Ballard Memorial | home | W | 42–13 | 5-0 | ||
| Fri, Sep 24, 2010 | Trigg County | home | W | 29–3 | 6-0 | ||
| Fri, Oct 1, 2010 | Reidland | away | W | 49–7 | 7-0 | ||
| Fri, Oct 15, 2010 | Caldwell County | away | W | 20–6 | 8-0 | ||
| Fri, Oct 22, 2010 | Heath | home | W | 49–0 | 9-0 | ||
| Fri, Oct 29, 2010 | Crittenden County | away | W | 21–10 | 10-0 | ||
| Fri, Nov 5, 2010 | Todd County Central | home | W | 49–0 | 11-0 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Fort Campbell | home | W | 49–15 | 12-0 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Owensboro Catholic | away | L | 22–29 | 12-1 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl |