Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 27, 2010 | Lloyd Memorial | away | W | 46–0 | 1-0 | ||
| Fri, Sep 3, 2010 | Bellevue | home | W | 54–7 | 2-0 | ||
| Fri, Sep 10, 2010 | Cooper | away | W | 28–20 | 3-0 | ||
| Fri, Sep 17, 2010 | Bourbon County | home | W | 52–7 | 4-0 | ||
| Fri, Sep 24, 2010 | Pendleton County | home | W | 55–0 | 5-0 | ||
| Fri, Oct 1, 2010 | Franklin County | away | W | 55–9 | 6-0 | ||
| Fri, Oct 8, 2010 | Dixie Heights | away | L | 20–47 | 6-1 | ||
| Fri, Oct 15, 2010 | Scott | home | W | 47–16 | 7-1 | ||
| Fri, Oct 22, 2010 | Withrow, OH | home | L | 12–49 | 7-2 | ||
| Fri, Oct 29, 2010 | Harrison County | away | W | 56–8 | 8-2 | ||
| Fri, Nov 5, 2010 | West Jessamine | home | L | 26–29 | 8-3 | 2010 Class 4A KHSAA Commonwealth Gridiron Bowl |