Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 27, 2010 | Leslie County | home | W | 51–7 | 1-0 | ||
| Fri, Sep 3, 2010 | Letcher County Central | away | W | 48–34 | 2-0 | ||
| Fri, Sep 10, 2010 | Paris | home | W | 54–13 | 3-0 | ||
| Fri, Sep 17, 2010 | Williamsburg | away | W | 55–8 | 4-0 | ||
| Fri, Sep 24, 2010 | Corbin | home | W | 35–28 | 5-0 | ||
| Fri, Oct 1, 2010 | Breathitt County | home | W | 40–20 | 6-0 | ||
| Fri, Oct 8, 2010 | Harlan | home | W | 50–20 | 7-0 | ||
| Fri, Oct 15, 2010 | Jenkins | home | W | 57–0 | 8-0 | ||
| Fri, Oct 22, 2010 | Pineville | away | W | 55–20 | 9-0 | ||
| Fri, Oct 29, 2010 | Clay County | away | W | 41–20 | 10-0 | ||
| Fri, Nov 5, 2010 | Allen Central | home | W | 64–6 | 11-0 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Pineville | home | W | 58–14 | 12-0 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Pikeville | away | W | 59–34 | 13-0 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 26, 2010 | Lexington Christian | home | W | 31–30 | 14-0 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Dec 3, 2010 | Mayfield | at houchens-l.t. smith stadium, wku | L | 6–47 | 14-1 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl |
