Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 27, 2010 | Paris | away | W | 53–6 | 1-0 | ||
| Fri, Sep 3, 2010 | Sheldon Clark | away | L | 12–25 | 1-1 | ||
| Fri, Sep 10, 2010 | Western Hills | home | W | 34–6 | 2-1 | ||
| Fri, Sep 17, 2010 | Franklin County | away | L | 12–20 | 2-2 | ||
| Fri, Sep 24, 2010 | Middlesboro | home | W | 48–27 | 3-2 | ||
| Fri, Oct 1, 2010 | Bracken County | away | W | 57–6 | 4-2 | ||
| Fri, Oct 8, 2010 | Eminence | home | W | 34–6 | 5-2 | ||
| Fri, Oct 15, 2010 | Gallatin County | home | W | 64–20 | 6-2 | ||
| Fri, Oct 22, 2010 | Trimble County | away | W | 62–0 | 7-2 | ||
| Fri, Oct 29, 2010 | Danville | away | L | 6–24 | 7-3 | ||
| Fri, Nov 5, 2010 | Bishop Brossart | home | W | 47–0 | 8-3 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Walton-Verona | home | W | 49–7 | 9-3 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Beechwood | home | L | 13–56 | 9-4 | 2010 Class 1A KHSAA Commonwealth Gridiron Bowl |