Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Fri, Aug 20, 2010 | Mason County | home | W | 21–14 | 1-0 | ||
| Sat, Aug 28, 2010 | Rockcastle County | home | W | 40–0 | 2-0 | ||
| Sat, Sep 4, 2010 | Pikeville | at corbin | W | 54–0 | 3-0 | ||
| Fri, Sep 10, 2010 | Somerset | home | L | 13–38 | 3-1 | ||
| Fri, Sep 17, 2010 | Southwestern | away | L | 19–22 | 3-2 | ||
| Fri, Sep 24, 2010 | Boyle County | away | L | 7–28 | 3-3 | ||
| Fri, Oct 8, 2010 | Bardstown | away | W | 59–13 | 4-3 | ||
| Fri, Oct 15, 2010 | Fort Knox | home | W | 49–0 | 5-3 | ||
| Fri, Oct 22, 2010 | Washington County | away | W | 55–35 | 6-3 | ||
| Fri, Oct 29, 2010 | Frankfort | home | W | 24–6 | 7-3 | ||
| Fri, Nov 5, 2010 | Metcalfe County | home | W | 49–0 | 8-3 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 12, 2010 | Green County | home | W | 28–14 | 9-3 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 19, 2010 | Monroe County | home | W | 48–21 | 10-3 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl | |
| Fri, Nov 26, 2010 | Owensboro Catholic | home | L | 42–61 | 10-4 | 2010 Class 2A KHSAA Commonwealth Gridiron Bowl |