Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Thu, Dec 2, 2021 | Lyon County | home | W | 58–25 | 1-0 | Marshall County Hoopfest | |
| Sat, Dec 4, 2021 | Clarksville Academy (Clarksville), TN | home | W | 54–38 | 2-0 | ||
| Fri, Dec 10, 2021 | Graves County | home | W | 50–36 | 3-0 | ||
| Sat, Dec 11, 2021 | Benton, IL | at mccracken county | W | 43–23 | 4-0 | ||
| Tue, Dec 14, 2021 | Murray | away | W | 57–23 | 5-0 | ||
| Tue, Dec 28, 2021 | Oldham County | at south warren | W | 69–35 | 6-0 | ||
| Wed, Dec 29, 2021 | Owensboro | at south warren | W | 56–19 | 7-0 | ||
| Wed, Dec 29, 2021 | Rockcastle County | at south warren | W | 53–36 | 8-0 | FirstBank Holiday Bash | |
| Thu, Dec 30, 2021 | Owensboro Catholic | at south warren | L | 57–62 | 8-1 | ||
| Mon, Jan 3, 2022 | Mayfield | away | W | 63–21 | 9-1 | ||
| Tue, Jan 4, 2022 | McCracken County | away | L | 34–56 | 9-2 | ||
| Fri, Jan 14, 2022 | Graves County | away | L | 36–40 | 9-3 | ||
| Sat, Jan 15, 2022 | McLean County | home | W | 61–20 | 10-3 | ||
| Fri, Jan 21, 2022 | Calloway County | home | W | 64–40 | 11-3 | ||
| Sat, Jan 22, 2022 | Bowling Green | home | L | 25–54 | 11-4 | ||
| Tue, Jan 25, 2022 | Christian Fellowship | home | W | 71–28 | 12-4 | ||
| Fri, Jan 28, 2022 | Paducah Tilghman | away | W | 70–27 | 13-4 | ||
| Sat, Jan 29, 2022 | McCracken County | home | L | 41–62 | 13-5 | ||
| Tue, Feb 8, 2022 | Murray | home | W | 66–22 | 14-5 | ||
| Thu, Feb 10, 2022 | Christian Fellowship | away | W | 60–20 | 15-5 | ||
| Fri, Feb 11, 2022 | Calloway County | away | W | 52–25 | 16-5 | ||
| Sat, Feb 12, 2022 | Hickman County | home | W | 53–15 | 17-5 | ||
| Tue, Feb 15, 2022 | Webster County | home | W | 49–42 | 18-5 | ||
| Sat, Feb 19, 2022 | Murray | at calloway county | W | 46–26 | 19-5 | 2022 4th District Girls Basketball Tournament | |
| Mon, Feb 21, 2022 | Calloway County | away | W | 59–34 | 20-5 | 2022 4th District Girls Basketball Tournament | |
| Sat, Feb 26, 2022 | Hickman County | at murray state university | W | 56–20 | 21-5 | 2022 1st Region Girls Basketball Tournament | |
| Thu, Mar 3, 2022 | McCracken County | at murray state university | L | 52–63 | 21-6 | 2022 1st Region Girls Basketball Tournament |