Schedule & results
| Date | Opponent | Site | Score | Record | Event | ||
|---|---|---|---|---|---|---|---|
| Tue, Nov 21, 2000 | Barbourville | home | W | 52–29 | 1-0 | ||
| Tue, Nov 28, 2000 | Williamsburg | away | L | 39–53 | 1-1 | ||
| Thu, Nov 30, 2000 | Oneida Baptist Institute | away | W | 57–45 | 2-1 | ||
| Sat, Dec 2, 2000 | Burgin | away | L | 52–54 | 2-2 | ||
| Mon, Dec 4, 2000 | Cordia | home | L | 45–70 | 2-3 | Three Rivers Conference Tournament | |
| Tue, Dec 5, 2000 | Piarist School | home | W | 80–24 | 3-3 | Three Rivers Conference Tournament | |
| Wed, Dec 6, 2000 | June Buchanan | home | L | 33–49 | 3-4 | Three Rivers Conference Tournament | |
| Mon, Dec 11, 2000 | Buckhorn | away | W | 63–59 | 4-4 | ||
| Tue, Dec 12, 2000 | Pineville | home | W | 51–49 | 5-4 | ||
| Mon, Dec 18, 2000 | Riverside Christian | away | W | 59–37 | 6-4 | ||
| Sat, Jan 6, 2001 | Cordia | away | L | 36–65 | 6-5 | ||
| Mon, Jan 8, 2001 | Oneida Baptist Institute | at oneida baptist | W | 53–31 | 7-5 | 13th Region All A Classic (1st round) | |
| Tue, Jan 9, 2001 | Middlesboro | away | L | 49–84 | 7-6 | 13th Region All A Classic (2nd round) | |
| Mon, Jan 15, 2001 | Letcher | away | L | 52–67 | 7-7 | ||
| Mon, Jan 22, 2001 | Oneida Baptist Institute | home | W | 53–32 | 8-7 | ||
| Thu, Jan 25, 2001 | June Buchanan | away | L | 36–42 | 8-8 | ||
| Mon, Jan 29, 2001 | Riverside Christian | home | W | 54–53 | 9-8 | ||
| Thu, Feb 1, 2001 | Cordia | home | L | 42–52 | 9-9 | ||
| Sat, Feb 3, 2001 | Buckhorn | home | W | 42–36 | 10-9 | ||
| Mon, Feb 5, 2001 | Letcher | home | L | 47–64 | 10-10 | ||
| Fri, Feb 9, 2001 | Pineville | away | L | 61–69 | 10-11 | (overtime) | |
| Mon, Feb 12, 2001 | Barbourville | away | W | 47–40 | 11-11 | ||
| Thu, Feb 15, 2001 | Williamsburg | home | L | 37–41 | 11-12 | ||
| Tue, Feb 20, 2001 | Kentucky School f/t Deaf | home | W | 52–43 | 12-12 | ||
| Thu, Feb 22, 2001 | June Buchanan | home | |||||
| Fri, Feb 23, 2001 | Piarist School | home | |||||
| Mon, Feb 26, 2001 | Pineville | at middlesboro | W | 60–48 | 13-12 | 2001 51st District Girls Basketball Tournament | |
| Fri, Mar 2, 2001 | Middlesboro | away | L | 44–72 | 13-13 | 2001 51st District Girls Basketball Tournament | |
| Thu, Mar 8, 2001 | Jackson County | at cawood | L | 30–103 | 13-14 | 2001 13th Region Girls Basketball Tournament |